Drosophila melanogaster Meigen (fruit fly) [DME]

FULL NAME: DNA polymerase alpha subunit B


DESCRIPTION:
May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery (By similarity).

STRUCTURE SIMILARITY:
Belongs to the DNA polymerase alpha subunit B family.


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MEEELKQQFD EMGVEPADAV LGRCAELAIT YNIHDATEFV EQWMAFSLSH LQGEDPAIEN
        70         80         90        100        110        120
LGDFERKVLQ LRKDKAGYKA TGQKAKSYGS PSVQDTSSLA TYGVMEDDPM LDDYVSESAV
       130        140        150        160        170        180
DSSALHTPKA KKQSDRTANL KGAALFSPAS YTPQSAKRKA GLETPSNSVA GKPGDIVDTF
       190        200        210        220        230        240
GHPKLLAGSS WQSQMEHTVP VTQKLLHNDA PLTIANLGYM NDLLTDRCHN LRVRFNQTGP
       250        260        270        280        290        300
ALVDKKLGQA GAAECIWYPQ DRQVLQSAGG LHAVGMIHSE DDGPLDAHSA FMAVLDDDVE
       310        320        330        340        350        360
DEMDPTLTLN FSRVKSASIF PGQVVLAKGF IPRGKTFMVE EIHTERKLTP ATPLQIDREL
       370        380        390        400        410        420
QFVVASGPFT DSTDLFYEPL HDLLKYLKDH RPDVLVLTGP FLDADHKMVG ELAETFDTFF
       430        440        450        460        470        480
EKMIGGIMES IGSHTAVLVV TSQKDAMALS VYPTPPPALR RTYPNLYMLP DPSLVDLDGF
       490        500        510        520        530        540
TLGVTSTDVV DHLLSHEFAV NAGERMHRAI NHLFHQGSFY PLYPPADEDM AYDSQLALKY
       550        560        570        580        590        600
AQLKQLPNVL ILPSDQRHFI RLVNDCLVIN PGRVADKKGG TFARFLVAPS VPGKAANMFN

SVACQVQRI     

Encoded by DNApol-alpha73 gene

FULL NAME: DNA polymerase alpha 73kD


OTHER NAME(S):
CG5923
Dmel\CG5923
Dmpol alpha
DNA pol-73
DNA polalpha
DNApol-alpha
DNApol-alpha72
DNApolalpha
Pol
pol alpha
POLA
polalpha
Polalpha


Nucleic acid sequence

        10         20         30         40         50         60
atggaggagg aattgaagca gcagttcgac gagatgggcg tggagccagc ggacgcagtt
        70         80         90        100        110        120
ctgggcaggt gtgcggagct ggccattacc tacaacatcc acgacgccac cgagttcgtg
       130        140        150        160        170        180
gagcagtgga tggccttcag tttgtcgcac ctccaaggcg aggatcctgc gatcgagaat
       190        200        210        220        230        240
ctgggcgact ttgagcgcaa ggtgttgcag ctgcggaagg acaaggcggg atacaaggca
       250        260        270        280        290        300
actggccaga aggcgaaatc atatggttcg ccctctgtac aggatacgag ctcactggcc
       310        320        330        340        350        360
acctatggcg tcatggagga cgatcccatg ctggatgact atgtcagcga atcggcagtg
       370        380        390        400        410        420
gactcctccg ctctgcacac gcccaaggcc aagaagcagt cggatcggac cgccaatctc
       430        440        450        460        470        480
aagggcgccg cactctttag ccccgccagc tatacacccc aatcggcaaa gaggaaagca
       490        500        510        520        530        540
ggtttagaaa caccatccaa ctcagtggcc ggcaagccgg gcgatatagt tgacaccttc
       550        560        570        580        590        600
ggacatccca aactcctggc tggctccagc tggcagtcac aaatggagca cacggttccg
       610        620        630        640        650        660
gtgactcaaa aactgctgca caacgacgcc ccgctgacca tcgcaaattt gggctacatg
       670        680        690        700        710        720
aacgacctgc tgaccgaccg atgtcacaac ctgcgcgtcc gcttcaacca aaccggtccg
       730        740        750        760        770        780
gcactagtgg acaagaaact tggacaagca ggcgcagccg agtgcatttg gtatccgcag
       790        800        810        820        830        840
gataggcagg tattgcagtc cgcaggtgga ctccacgcgg tgggaatgat tcattccgag
       850        860        870        880        890        900
gacgatggcc cactggacgc ccactccgca tttatggccg ttttagatga cgatgtagaa
       910        920        930        940        950        960
gatgaaatgg acccaacgct cacgctcaac ttctccaggg tcaagtctgc cagcatattc
       970        980        990       1000       1010       1020
ccaggtcaag tggtgctcgc caaagggttc atacccaggg gcaaaacctt catggtagag
      1030       1040       1050       1060       1070       1080
gagatacaca cagagcgcaa actgacgcca gcaacgccac tgcaaataga cagggagctt
      1090       1100       1110       1120       1130       1140
cagtttgtgg tggcctccgg accctttacg gacagtacgg atctcttcta cgaaccgctg
      1150       1160       1170       1180       1190       1200
cacgacctgc tcaagtacct caaggatcac agacctgacg tgctggtgct cacgggacca
      1210       1220       1230       1240       1250       1260
ttcctggatg ccgatcacaa gatggtcggc gaactggccg agaccttcga tacattcttc
      1270       1280       1290       1300       1310       1320
gagaagatga ttgggggaat aatggagtcg attggtagtc acacagcagt gctggtggtg
      1330       1340       1350       1360       1370       1380
accagtcaga aggatgccat ggctctttcc gtatatccaa cgccgccgcc cgctctgcgc
      1390       1400       1410       1420       1430       1440
agaacctatc caaatctata catgctgccc gatccatctc tggtggactt ggatggcttt
      1450       1460       1470       1480       1490       1500
acgctgggcg ttacctcaac cgacgtggtg gaccacctgt tgagtcacga gtttgctgtg
      1510       1520       1530       1540       1550       1560
aatgccggcg agcggatgca cagggccatc aaccacttgt tccaccaggg ctccttctat
      1570       1580       1590       1600       1610       1620
cctttgtatc cgccggcgga cgaagacatg gcctacgatt cccagctggc gttgaaatat
      1630       1640       1650       1660       1670       1680
gcacagctca aacagctacc aaatgtgctc atcttgccca gcgatcagcg gcatttcatc
      1690       1700       1710       1720       1730       1740
cgcttggtca acgactgcct ggtgatcaat cccggccgtg tcgcggacaa gaagggtgga
      1750       1760       1770       1780       1790       1800
actttcgccc gattcctggt ggcgccttcg gtgccgggaa aggcggccaa catgttcaac
      1810       1820       1830
agtgtggcgt gtcaagtcca acgcatctaa   

Last modification date: Oct. 2, 2011