Mus musculus L. (mouse) [MMU]

FULL NAME: Ribonuclease H2 subunit C


DESCRIPTION:
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.

STRUCTURE SIMILARITY:
Belongs to the RNase H2 subunit C family.


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MKNPEEAADG KQRIHLRPGS LRGAAPAKLH LLPCDVLVSR PAPVDRFFTP AVRHDADGLQ
        70         80         90        100        110        120
ASFRGRGLRG EEVAVPPGFA GFVMVTEEKG EGLIGKLNFS GDAEDKADEA QEPLERDFDR
       130        140        150        160
LIGATGSFSH FTLWGLETVP GPDAKVHRAL GWPSLAAAIH AQVPED 

Encoded by Rnaseh2c gene

FULL NAME: ribonuclease H2, subunit C


OTHER NAME(S):
1500026D16Rik
AYP1


Nucleic acid sequence

        10         20         30         40         50         60
atgaagaacc cggaggaagc ggcagacggg aaacagcgta ttcacctgcg ccctggctcg
        70         80         90        100        110        120
ctgcgtggtg ccgcaccggc taagctgcac ctcctgccct gcgacgttct agtcagccgg
       130        140        150        160        170        180
ccggccccgg tagatcgctt cttcacgccc gccgtccgcc acgatgcaga cgggctacag
       190        200        210        220        230        240
gcgtcgtttc gcggtcgcgg cctgcggggc gaggaggtag ctgtgccgcc agggtttgcg
       250        260        270        280        290        300
ggattcgtga tggtgacgga ggagaaggga gaggggttga tagggaaact gaacttctcc
       310        320        330        340        350        360
ggggacgcgg aggacaaagc ggacgaggcg caggagccgc tggagcggga cttcgaccgc
       370        380        390        400        410        420
cttatcgggg ccaccggcag cttcagccat ttcaccttgt ggggtctgga aacggtcccg
       430        440        450        460        470        480
ggtccagatg ccaaagtgca tagggcccta ggttggccca gcctcgcagc agcgattcac
       490        500
gcccaggtcc ctgaggactg a   

Last modification date: Oct. 2, 2011