Mus musculus L. (mouse) [MMU]

FULL NAME: Replication factor C subunit 4


DESCRIPTION:
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template (By similarity).

MISCELLANEOUS:
Despite of the presence of a putative ATP-binding motif, this protein does not bind ATP (By similarity).


STRUCTURE SIMILARITY:
Belongs to the activator 1 small subunits family.


RELATED PATHWAY(S):
DNA replication
nucleotide excision repair (NER)
mismatch repair (MMR)


Amino acids sequence

        10         20         30         40         50         60
MQAFLKGTSV SAKAQLTKDR GTPATAGSSG ETKKVKPVPW VEKYRPKCVD EVAFQDEVVA
        70         80         90        100        110        120
VLRKSLEGAD LPNLLFYGPP GTGKTSTILA AARELFGPEL FRLRVLELNA SDERGIQVVR
       130        140        150        160        170        180
EKVKNFAQLT VSGSRSDGKP CPPFKIVILD EADSMTSAAQ AALRRTMEKE SKTTRFCLIC
       190        200        210        220        230        240
NYVSRIIEPL TSRCSKFRFK PLSDKIQQER LLDIAEKENV KIGNEEIAYL VKISEGDLRK
       250        260        270        280        290        300
AITFLQSATR LTGGKEVSED VITDIAGVIP AATIDGIFTA CHSGSFDKLE AVVKNLIDEG
       310        320        330        340        350        360
HAATQLVNQL HDAIIENENL SDKHKSIITE KLAEVDKCLA DGADEHLQLM SLCATVMQQL

TQNC     

Encoded by Rfc4 gene

FULL NAME: replication factor C (activator 1) 4


OTHER NAME(S):
A1
AI894123
AU040575
RFC37


Nucleic acid sequence

        10         20         30         40         50         60
atgcaggcat ttctgaaagg cacatctgtc agtgccaaag cacaactgac caaggaccgg
        70         80         90        100        110        120
gggacacctg ccactgcagg aagcagtgga gaaaccaaga aagtcaaacc agttccttgg
       130        140        150        160        170        180
gtggaaaaat accgtccaaa gtgtgtggat gaagtggctt tccaggacga agtggttgca
       190        200        210        220        230        240
gtgctgagaa agtccttaga aggagctgac cttcctaatc tcttgttcta tgggccacct
       250        260        270        280        290        300
ggaactggca aaacatccac cattttggca gcagctagag agctctttgg gcctgaactc
       310        320        330        340        350        360
tttcgattaa gagtccttga gttaaatgca tctgatgaac gtggaataca agtagtccga
       370        380        390        400        410        420
gagaaagtga aaaattttgc tcagttaact gtatcaggaa gtcgttcaga tgggaagcca
       430        440        450        460        470        480
tgtcctccct ttaagattgt aattctggat gaagcagatt cgatgacttc agctgctcag
       490        500        510        520        530        540
gcagctttaa ggcgtaccat ggaaaaagaa tcaaaaacaa ccagattctg cctcatctgt
       550        560        570        580        590        600
aactatgtca gtcgaataat tgaacccctc acttctagat gttcaaaatt ccgcttcaag
       610        620        630        640        650        660
cctctgtcag ataagattca acaggagcga ttactggata ttgctgagaa ggaaaatgtc
       670        680        690        700        710        720
aaaattggca atgaggaaat agcgtatctt gttaagatat cagaaggaga tttacggaaa
       730        740        750        760        770        780
gccatcacat ttcttcagag tgccactcga ctaacaggtg gaaaggaagt ctctgaagat
       790        800        810        820        830        840
gtgatcacag acattgctgg ggtaatacca gctgcaacca ttgatggaat attcactgca
       850        860        870        880        890        900
tgtcacagtg gctcttttga caaactagaa gctgtggtaa agaacctcat agatgaagga
       910        920        930        940        950        960
catgcagcta ctcagcttgt caatcaactt catgatgcaa ttatagaaaa tgaaaatctg
       970        980        990       1000       1010       1020
tctgataaac acaagtccat tatcacagag aaacttgctg aagtagacaa gtgcttggca
      1030       1040       1050       1060       1070       1080
gatggtgcag atgaacacct gcagttgatg agcctttgtg caactgtgat gcagcagcta
      1090
actcagaact gttag    

Last modification date: Oct. 2, 2011