Mus musculus L. (mouse) [MMU]

FULL NAME: DNA polymerase delta subunit 2


DESCRIPTION:
The function of the small subunit is not yet clear.

STRUCTURE SIMILARITY:
Belongs to the DNA polymerase delta/II small subunit family.


CATALYTIC ACTIVITY:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).


RELATED PATHWAY(S):
DNA replication
base excision repair (BER)
nucleotide excision repair (NER)
mismatch repair (MMR)
homologous recombination (HR)


Amino acids sequence

        10         20         30         40         50         60
MFSEQAAQRA HTLLAPPSAS NATFARVPVA TYTNSSQPFR LGERSFNRQY AHIYATRLIQ
        70         80         90        100        110        120
MRPFLVSRAQ QHWGSRVEVK KLCELQPGEQ CCVVGTLFKA MSLQPSILRE ISEEHNLVPQ
       130        140        150        160        170        180
PPRSKYIHPD DELVLEDELQ RIKLKGTIDV SKLVTGTVLA VLGSAKDDGR FQVEDHCFAD
       190        200        210        220        230        240
LAPQKPVPPL DTDRFVLLVS GLGLGGGGGE SLLGTQLLVD VVTGQLGDEG EQCSAAHVSR
       250        260        270        280        290        300
VILAGNLLSH NTQSRDSINK AKYLTKKTQA ASVEAVKMLD EILLQLSASV PVDVMPGEFD
       310        320        330        340        350        360
PTNYTLPQQP LHPCMFPLAT AYSTLQLVTN PYQATIDGVR FLGTSGQNVS DIFRYSSMED
       370        380        390        400        410        420
HLEILEWTLR VRHISPTAPD TLGCYPFYKT DPFIFPECPH VYFCGNTPSF GSKIIRGPED
       430        440        450        460
QVVLLVAVPD FSSTQTACLV NLRSLACQPI SFAGFGAEQE DLEGLGLGP 

Encoded by Pold2 gene

FULL NAME: polymerase (DNA directed), delta 2, regulatory subunit


OTHER NAME(S):
50kDa
p50
po1D2


Nucleic acid sequence

        10         20         30         40         50         60
atgttctccg agcaggcagc acagagggcc cacactctgc tcgccccgcc ctctgccagc
        70         80         90        100        110        120
aatgccacct ttgcccgggt acctgtggca acttacacca actcctcaca gcccttccga
       130        140        150        160        170        180
ctgggagagc gcagctttaa ccggcagtac gcccatattt atgccacccg cctcatccag
       190        200        210        220        230        240
atgagaccgt tcctggtgag ccgggcgcag caacactggg gcagccgagt tgaagtgaag
       250        260        270        280        290        300
aagttgtgtg agctgcagcc tggggagcag tgctgtgtgg tgggcacgct gttcaaagcc
       310        320        330        340        350        360
atgtccctcc aaccctccat cctgcgggag atcagcgagg agcacaacct ggtcccccag
       370        380        390        400        410        420
cctccacgga gcaaatatat ccacccggat gacgagctgg tcttagaaga tgagctgcag
       430        440        450        460        470        480
cgtatcaaac tgaaaggcac cattgatgtg tcaaagctgg tcacaggaac ggtcttggcc
       490        500        510        520        530        540
gtgttgggct ctgcgaaaga tgacgggagg tttcaggttg aagaccactg ctttgctgac
       550        560        570        580        590        600
ctggctccac agaagccggt acccccactt gacacagaca gatttgtgct actggtatcc
       610        620        630        640        650        660
ggactgggcc tgggcggtgg tggcggggag agcctcctgg gcacccagct gctggtggac
       670        680        690        700        710        720
gtggtgacgg gacagcttgg ggacgaagga gaacagtgca gtgctgccca cgtctctcga
       730        740        750        760        770        780
gtcatcctcg caggcaacct gctcagccat aacacccaga gcagagactc catcaacaag
       790        800        810        820        830        840
gccaaatacc ttaccaagaa aacccaggca gccagtgtgg aggcagtcaa aatgctggac
       850        860        870        880        890        900
gagatccttc tgcaactgag tgcctcggta ccggtggatg tgatgccagg cgagtttgat
       910        920        930        940        950        960
cccaccaact atacactccc gcagcagccc ctgcacccct gcatgttccc gctggccacc
       970        980        990       1000       1010       1020
gcctactcca cactccagct ggtcaccaac ccataccaag ccaccattga tggagtaagg
      1030       1040       1050       1060       1070       1080
ttcctgggga catctggaca gaacgtgagt gatatcttcc ggtatagcag catggaagac
      1090       1100       1110       1120       1130       1140
cacttagaga tcctagagtg gaccctgcgg gttcgtcaca tcagccccac ggctccagac
      1150       1160       1170       1180       1190       1200
accctagggt gctacccctt ctacaaaacc gacccgttca tctttccgga atgtcctcac
      1210       1220       1230       1240       1250       1260
gtctacttct gtggcaacac ccccagcttt ggttccaaaa tcatccgagg tcctgaggac
      1270       1280       1290       1300       1310       1320
caggtagtgc tgttagtggc tgttcctgac ttcagttcca cacagacggc ctgcctagtg
      1330       1340       1350       1360       1370       1380
aacttacgca gcctggcctg ccagcctatc agctttgcgg gcttcggggc agagcaagag
      1390       1400       1410
gacctggagg gcctggggct gggtccctag   

Last modification date: Oct. 2, 2011