Mus musculus L. (mouse) [MMU]

FULL NAME: DNA primase large subunit


DESCRIPTION:
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

STRUCTURE SIMILARITY:
Belongs to the eukaryotic-type primase large subunit family.


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MQFSGRIRKK LRLAGDQRNA SYPHSLQFYL QPPTENISLT EFENLAFDRV KLLKAIENLG
        70         80         90        100        110        120
VSYVKGTEQY QSKLEAEIRK LKFSYRENLE DEYEPRRRDH ISHFILRLAY CQSEDLRRWF
       130        140        150        160        170        180
IQQEMDLLRF RFSILPKDKV QSFLKDSHLH FEAISDEEKT LREQDIMASS PSLSGIKLES
       190        200        210        220        230        240
ESVYKVPFAD ALDLFRGRKV YLEDGFAYVP LKDIVAIILN EFRATLSKAL ALTARSLPAV
       250        260        270        280        290        300
QSDERLQPLL NHLSHSYTGQ DYSTQKNTGK ISLDQIDSLS TKSFPPCMRQ LHKALRENHH
       310        320        330        340        350        360
LRHGGRMQYG LFLKGIGLTL EQALQFWKQE FIRGKMDPDK FDKGYSYNIR HSFGKEGKRT
       370        380        390        400        410        420
DYTPFSCMKI ILTNPPGQGD YHGCPFRHSD AELLKQKMQS YKIPASGISQ ILDLVKGNHY
       430        440        450        460        470        480
QVACQKYFEM THNVDDCGFS LNHPNQFFFE SQRILTGGKD IKKEISQPET PQHKPSTQKT
       490        500
RDAASALASL DSSLEMDLEG LEEYF   

Encoded by Prim2 gene

FULL NAME: DNA primase, p58 subunit


OTHER NAME(S):
AI323589


Nucleic acid sequence

        10         20         30         40         50         60
atgcagttct caggaaggat ccggaagaag ctgcgattgg cgggtgacca gagaaatgct
        70         80         90        100        110        120
agttaccctc acagccttca gttttacctg cagccgccta ctgaaaacat atcgttgacg
       130        140        150        160        170        180
gagtttgaaa acttggcttt tgacagagtt aaattgctta aagcaattga gaacctcggt
       190        200        210        220        230        240
gtgagctatg tgaaaggaac cgaacaatac cagagtaaat tggaggccga gattcgaaag
       250        260        270        280        290        300
ctcaagtttt cctacagaga gaacctggag gatgagtatg agccacggcg aagggaccac
       310        320        330        340        350        360
atctcccact ttatcctacg cctcgcgtac tgccagtcgg aagatcttag acgatggttt
       370        380        390        400        410        420
attcaacaag aaatggatct gcttcggttt cgattcagta ttttaccaaa ggataaagtc
       430        440        450        460        470        480
cagagtttct tgaaggatag tcatttgcat tttgaggcta tcagtgacga ggagaagacc
       490        500        510        520        530        540
cttcgggaac aggatatcat ggcgtcctct ccaagcctaa gtgggatcaa gttggagtca
       550        560        570        580        590        600
gagtcagttt ataaggtccc ctttgctgat gctctggacc tgttcagagg aaggaaagtc
       610        620        630        640        650        660
tacttggaag atggctttgc ttatgtgcca cttaaggaca tcgtggccat tatcttgaac
       670        680        690        700        710        720
gagtttagag ccacgctgtc taaggctttg gcactaacgg ccaggtcgct gcctgctgtg
       730        740        750        760        770        780
cagtccgatg aacgacttca gcctctgctc aaccacctca gtcattctta cactggtcaa
       790        800        810        820        830        840
gattatagta cccagaagaa caccggcaag atttccttag atcagattga ttcgctgtct
       850        860        870        880        890        900
acaaaatcct tcccaccttg catgcgtcag ctgcacaagg cgctgaggga gaaccaccat
       910        920        930        940        950        960
ctccgtcacg gaggccggat gcagtacggc ctgttcctca agggcattgg gctaacgctg
       970        980        990       1000       1010       1020
gagcaggcat tgcagttctg gaagcaggag tttatcagag gaaagatgga cccagacaag
      1030       1040       1050       1060       1070       1080
tttgataaag gttactctta caatatccgg catagcttcg gaaaggaagg caagaggaca
      1090       1100       1110       1120       1130       1140
gactatacgc ctttcagttg catgaagatt atcctgacca acccaccagg ccaaggggat
      1150       1160       1170       1180       1190       1200
tatcatgggt gccccttccg tcacagtgat gcagagctgc tgaagcagaa gatgcagtcc
      1210       1220       1230       1240       1250       1260
tacaagatcc ctgcctcggg gatcagccag attttggatt tggtaaaggg gaatcattac
      1270       1280       1290       1300       1310       1320
caagtagcct gtcagaagta cttcgagatg acacataatg tggacgattg tggcttttct
      1330       1340       1350       1360       1370       1380
ttgaatcatc caaatcagtt cttttttgag agccagcgca tcctaactgg tggcaaagat
      1390       1400       1410       1420       1430       1440
atcaagaagg aaatcagtca gccagaaaca cctcagcaca aacctagcac ccagaagacc
      1450       1460       1470       1480       1490       1500
agggatgctg catctgcgct ggcctcccta gactcctccc tggaaatgga cctggagggg
      1510
ctggaagagt acttttag    

Last modification date: Oct. 2, 2011