Mus musculus L. (mouse) [MMU]

FULL NAME: DNA primase small subunit


DESCRIPTION:
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

MISCELLANEOUS:
The bound zinc ion is not a cofactor. It is bound to a zinc knuckle motif that may be involved in sequence recognition and the binding of ssDNA (By similarity).


STRUCTURE SIMILARITY:
Belongs to the eukaryotic-type primase small subunit family.


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MEPFDPAELP ELLKLYYRRL FPYAQYYRWL NYGGVTKNYF QHREFSFTLK DDIYIRYQSF
        70         80         90        100        110        120
NNQSELEKEM QKMNPYKIDI GAVYSHRPNQ HNTVKLGAFQ AQEKELVFDI DMTDYDDVRR
       130        140        150        160        170        180
CCSSADICSK CWTLMTMAMR IIDRALKEDF GFKHRLWVYS GRRGVHCWVC DESVRKLSSA
       190        200        210        220        230        240
VRSGIVEYLS LVKGGQDVKK KVHLNEKVHP FVRKSINIIK KYFEEYALVG QDILENKENW
       250        260        270        280        290        300
DKILALVPET IHDELQRGFQ KFHSSPQRWE HLRKVANSSQ NMKNDKCGPW LEWEVMLQYC
       310        320        330        340        350        360
FPRLDVNVSK GVNHLLKSPF SVHPKTGRIS VPIDFHKVDQ FDPFTVPTIS AICRELDMVS
       370        380        390        400        410
THEKEKEENE ADSKHRVRGY KKTSLAPYVK VFEQFLENLD KSRKGELLKK SDLQKDF

Encoded by Prim1 gene

FULL NAME: DNA primase, p49 subunit


OTHER NAME(S):
AI324982
MGC107288


Nucleic acid sequence

        10         20         30         40         50         60
atggagccat ttgatcctgc ggagctgccg gagctactca agctttatta ccgaaggctc
        70         80         90        100        110        120
tttccctacg cccagtacta tcgctggctc aactatggcg gagtgacaaa gaattacttt
       130        140        150        160        170        180
caacaccgtg aattttcatt cacactgaaa gatgatattt acattcgcta ccagtccttc
       190        200        210        220        230        240
aacaaccaga gtgaactgga gaaggagatg cagaaaatga atccatataa gattgatata
       250        260        270        280        290        300
ggcgcagtat attctcacag acccaatcaa cacaatacag tgaagctggg agctttccag
       310        320        330        340        350        360
gcccaggaga aagaactggt ctttgacatc gacatgacag actacgatga cgtaaggaga
       370        380        390        400        410        420
tgctgcagtt ctgcagacat atgttccaaa tgctggactc tcatgacaat ggccatgcgc
       430        440        450        460        470        480
atcatagacc gggcattgaa ggaggacttt ggatttaagc accgcctctg ggtctattca
       490        500        510        520        530        540
ggaaggagag gtgtgcactg ttgggtctgt gatgaatccg ttcgaaagct gtcctctgct
       550        560        570        580        590        600
gtgcgctccg ggatcgtgga gtacttgagt cttgtaaagg gtggtcaaga tgttaaaaag
       610        620        630        640        650        660
aaagttcacc taaatgagaa agttcaccct tttgtcagaa aatctataaa cataattaaa
       670        680        690        700        710        720
aagtactttg aggaatatgc cttagtcggc caagatattc ttgaaaataa agaaaactgg
       730        740        750        760        770        780
gataagattt tagcccttgt tcctgagaca attcatgatg agctgcaaag agggttccag
       790        800        810        820        830        840
aagttccaca gttcacctca gcgctgggaa cacctgagga aagtggccaa ctcatctcag
       850        860        870        880        890        900
aatatgaaga acgataagtg cggcccctgg ctggagtggg aggtcatgct ccagtactgt
       910        920        930        940        950        960
ttcccacgcc tggatgtcaa cgtcagcaag ggagtcaatc acttactgaa gagccctttc
       970        980        990       1000       1010       1020
agtgttcatc ccaagacagg tcggatttct gtgcctatcg attttcataa agtggatcaa
      1030       1040       1050       1060       1070       1080
tttgatccgt ttactgtccc aactataagt gccatctgcc gggaattgga tatggtttcc
      1090       1100       1110       1120       1130       1140
actcatgaga aggaaaagga ggagaatgaa gctgacagca aacacagagt cagaggttac
      1150       1160       1170       1180       1190       1200
aagaagacca gtctagcacc gtatgtgaaa gtatttgaac agtttcttga aaacctggat
      1210       1220       1230       1240       1250
aaatcccgga aaggggaact tctcaagaag agcgatttac aaaaagattt ctga

Last modification date: Oct. 2, 2011