Caenorhabditis elegans Maupas (nematode) [CEL]

FULL NAME: DNA primase small subunit


DESCRIPTION:
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication (By similarity).

MISCELLANEOUS:
The bound zinc ion is not a cofactor. It is bound to a zinc knuckle motif that may be involved in sequence recognition and the binding of ssDNA (By similarity).


STRUCTURE SIMILARITY:
Belongs to the eukaryotic-type primase small subunit family.


SUBUNIT STRUCTURE:
Heterodimer of a small subunit and a large subunit.


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MSYNSIRLPQ DLPIYYKNFF PVKPFTKWLR YGQNNGDYFN RREFAFILAD DVHIRYRSYN
        70         80         90        100        110        120
DEHAFFKALS STNPEKLDIG AVYNHEPINN KRHTDYQAVE RELVFDIDLT DYDPVRNCCK
       130        140        150        160        170        180
DATVCPKCWK FMVLAVKILD FQLEDMFDFK ARMWVFSGRR GVHCWVGDKK ARMLNNYQRS
       190        200        210        220        230        240
AIATRLNLFK KNGQCEVTEG RAKMTKVPPI VRDAFNVALK DGVFEKMIYD QGWLDKEDFI
       250        260        270        280        290        300
TEYKFMSEVG RDDLRSLSET YKTPQERWNM IRGLFDDDYR KSLSPKDGLL DFKMQGRDRN
       310        320        330        340        350        360
YLLYFVLQRC YPRLDVNVST GTNHLLKSPF CIHPKTGNVA VPLNVGKIEE FDVSKCPRID
       370        380        390        400        410
HVVEELSSLL AERGNDENED SKNRKFLAYK HGALAPYVEN FEKFVSACIS 

Encoded by pri-1 gene

FULL NAME: DNA PRImase homolog


Nucleic acid sequence

        10         20         30         40         50         60
atgtcttata actccatcag acttccacaa gatttgccaa tatactacaa aaacttcttc
        70         80         90        100        110        120
ccagtcaaac cattcacaaa atggctccgc tacggacaaa ataacggaga ctatttcaac
       130        140        150        160        170        180
cgccgagaat tcgcattcat tctggcagat gacgttcata tcagatatcg tagttacaat
       190        200        210        220        230        240
gacgaacacg catttttcaa agcactttca agtactaacc cggaaaaact tgatattgga
       250        260        270        280        290        300
gctgtctaca atcacgagcc aattaataac aagagacata cagattatca agctgtggaa
       310        320        330        340        350        360
cgagaattgg tttttgatat cgatttgacc gactacgatc cagttcgtaa ttgttgcaaa
       370        380        390        400        410        420
gatgccaccg tctgcccaaa atgctggaaa ttcatggttc tcgctgttaa aatcttggat
       430        440        450        460        470        480
ttccaactgg aagatatgtt cgatttcaaa gcacgaatgt gggtcttctc tggtagacgt
       490        500        510        520        530        540
ggagtacatt gttgggtcgg tgacaaaaaa gcgaggatgt tgaacaatta tcaaagatct
       550        560        570        580        590        600
gcaatcgcga ccagactcaa tttgttcaag aaaaatggcc aatgtgaggt gactgaaggt
       610        620        630        640        650        660
cgggccaaaa tgacgaaagt tccgccgatt gtgcgtgacg cgtttaacgt tgcattgaaa
       670        680        690        700        710        720
gatggagttt tcgagaagat gatctatgac cagggatggc tggataagga agattttatc
       730        740        750        760        770        780
acagagtaca agtttatgtc agaagtaggc agagatgact tgcgtagcct ttccgagact
       790        800        810        820        830        840
tacaaaactc cacaagaacg ctggaacatg attcgtgggc tttttgatga cgactatcgc
       850        860        870        880        890        900
aaatcgcttt ctccgaagga cggtcttctc gattttaaaa tgcaaggtcg cgaccgaaat
       910        920        930        940        950        960
tatcttctct actttgttct tcaacgatgc tatccacgtc ttgatgttaa tgtatctaca
       970        980        990       1000       1010       1020
ggaacaaatc acttgctcaa atccccattc tgcattcatc caaagaccgg aaacgttgca
      1030       1040       1050       1060       1070       1080
gttcctctga atgtcggtaa aattgaagag ttcgatgtaa gcaaatgtcc tcgaattgat
      1090       1100       1110       1120       1130       1140
catgtcgtgg aagagttgag cagtcttttg gctgaacgag gaaacgacga gaacgaggat
      1150       1160       1170       1180       1190       1200
tcgaagaatc gaaaattcct ggcgtacaag catggagctc tcgcacctta cgttgaaaac
      1210       1220       1230
tttgaaaagt ttgtatcggc ttgcatttca taa  

Last modification date: Oct. 7, 2011