Caenorhabditis elegans Maupas (nematode) [CEL]

FULL NAME: DNA polymerase alpha subunit B


DESCRIPTION:
May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery (By similarity).

STRUCTURE SIMILARITY:
Belongs to the DNA polymerase alpha subunit B family.


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MAYEFDLEDF NDNLEPFGFN CPAKDHFIEK LEGLCKTFRK SGEDIVDDVV SVMSNLGQKS
        70         80         90        100        110        120
VDSGILAKLE ENLEAQAQKT VHTPRSVKKP ARGRVPLAEK SGFILSGDPD DIEKPSHHLT
       130        140        150        160        170        180
NSAIAKLEGH FLDFSPFPGS PANEKFLKRA DPSHVVTTIR GKKYQDKGLK GSTKSDDTIR
       190        200        210        220        230        240
IISKTPSTLY GGDKSSMVIE AKAQRMADIA HRIQKSFEEI VDWGNPSIPS VDVVYTYGQV
       250        260        270        280        290        300
IHDETKDNEK FGEHSVALMI NDEDGTMIRM DFSKMTEDIT LFPGQIIAVR GTNETGEELQ
       310        320        330        340        350        360
VDKIFQPAAL PVNPVETDTT KEIWFACGPY TATDNCGYEH LCELLDKVVA EKPDILMLAG
       370        380        390        400        410        420
PFVDKKNTFL NKPTFNITYD NLLEDLLLKV KETLVGTKTQ VIIQPNASRD LCVPPVFPSA
       430        440        450        460        470        480
PFQQNRKLDK IKKELIFVAD PCIFRISGVE VAMTSSEPIQ ALSNTEFHRS ANQENIDRVA
       490        500        510        520        530        540
RLSSHLLTQQ CMYPLEPTEV PASMGDLLDV CCIGSTPHIV FAPTKLAPSA KCVNGSVFIN
       550        560        570        580
SSTLAKGPTG NYAKMSINLN AGELMPGETV ADYAQIQILK I 

Encoded by div-1 gene

FULL NAME: cell DIVision defective


Nucleic acid sequence

        10         20         30         40         50         60
atggcatacg agttcgattt ggaagatttt aacgataatc ttgagccatt tggctttaat
        70         80         90        100        110        120
tgtcccgcaa aagatcattt tattgaaaaa ttagaaggac tatgcaaaac gttccggaag
       130        140        150        160        170        180
agcggtgagg atattgtcga tgatgtcgtt tcggtgatga gcaatcttgg gcaaaagtcc
       190        200        210        220        230        240
gttgactctg gaattttggc gaaattagag gagaatctgg aggctcaggc ccagaaaact
       250        260        270        280        290        300
gtgcacacgc cgagatctgt gaaaaaaccg gcacgcggcc gtgttccgct cgcagaaaaa
       310        320        330        340        350        360
agtggattca tcctaagtgg cgaccccgat gacattgaaa aaccgtcaca tcacctcaca
       370        380        390        400        410        420
aattcagcga ttgcaaagct tgaaggacat tttctcgact tttcaccatt tcccggttcc
       430        440        450        460        470        480
ccggctaatg agaaattcct gaaaagagcc gatccatcac atgttgtcac aactattcga
       490        500        510        520        530        540
gggaagaagt atcaggataa aggattgaaa ggatcgacaa aaagcgatga tactataaga
       550        560        570        580        590        600
attatctcga aaacgccgag tacattgtat ggtggagata aatcttctat ggttattgaa
       610        620        630        640        650        660
gcaaaagcac aacgaatggc agatatcgct caccgtatcc aaaaatcatt cgaagaaatt
       670        680        690        700        710        720
gtcgattggg gaaatccatc gataccgtca gttgatgttg tatatacata tggacaagtg
       730        740        750        760        770        780
attcatgatg agacaaagga taatgagaaa tttggagagc attctgttgc tcttatgatt
       790        800        810        820        830        840
aacgacgaag acggcacaat gatccgaatg gattttagta aaatgacaga agatataact
       850        860        870        880        890        900
ctcttccccg gacaaattat cgctgttcgt gggaccaatg agactggcga ggagcttcaa
       910        920        930        940        950        960
gttgacaaga tcttccagcc agcggcactt ccagtgaatc ccgttgaaac tgacactacg
       970        980        990       1000       1010       1020
aaagaaatct ggtttgcgtg tggtccgtac actgcgacgg acaattgtgg gtatgagcat
      1030       1040       1050       1060       1070       1080
ctctgtgagc ttttggacaa agtcgttgcc gagaagcccg atattttgat gctggctggg
      1090       1100       1110       1120       1130       1140
ccatttgtgg ataagaagaa cacgtttttg aataagccca cttttaatat tacctatgac
      1150       1160       1170       1180       1190       1200
aatttgttgg aggatttgct cttgaaagtt aaggagacgc ttgtcggcac aaaaacgcaa
      1210       1220       1230       1240       1250       1260
gtgatcattc aaccgaacgc atcccgtgat ctttgtgttc ctccggtctt cccaagtgct
      1270       1280       1290       1300       1310       1320
ccgttccaac agaaccgaaa actcgataaa atcaagaaag agctgatctt cgtcgccgat
      1330       1340       1350       1360       1370       1380
ccatgcattt tccgaatcag cggtgtcgag gtggcaatga ctagcagtga gcctattcaa
      1390       1400       1410       1420       1430       1440
gcgttgagca atacggaatt ccatcgatcc gcaaatcagg agaacattga tcgtgtcgcc
      1450       1460       1470       1480       1490       1500
cgtctcagca gtcatcttct cactcagcag tgcatgtatc cattggagcc aacggaagtt
      1510       1520       1530       1540       1550       1560
ccagcgtcca tgggagattt gctcgatgtc tgctgtatcg gctcgactcc tcatatcgtt
      1570       1580       1590       1600       1610       1620
tttgcaccga caaagcttgc gccatcagca aaatgtgtga atggaagtgt gttcattaac
      1630       1640       1650       1660       1670       1680
tcatctacac tcgccaaagg gccaacagga aactatgcaa aaatgtcgat taacctgaat
      1690       1700       1710       1720       1730       1740
gccggagaac tcatgcccgg ggagacggtc gccgattatg ctcagattca aattttgaaa

atttaa     

Last modification date: Oct. 2, 2011