Caenorhabditis elegans Maupas (nematode) [CEL]

FULL NAME: DNA polymerase


STRUCTURE SIMILARITY:
Belongs to the DNA polymerase type-B family.


CATALYTIC ACTIVITY:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MSDSENHAES DVRRSSRRCG VSQKKSKELS AIEQLKLARS TGKAYRPELD VEDVYDTVDD
        70         80         90        100        110        120
DEYEKIVAKR QKDNFIVDDD GMGYVDNGVD FEDDYEDDYA PSSSKNSNSS KKGEKKPKKD
       130        140        150        160        170        180
KKKGGLHAFL STTSTKKPID ESVVKAEFDD DEEVKNMLEQ LGSSDEEAEE KPKATPANPF
       190        200        210        220        230        240
KRGRKFDSPS GSDSLAPRPI AKKAKREATG LAEHKFQRHV KVDEDEDYGI PDDYPVASPV
       250        260        270        280        290        300
TSPVKTEKMA EVEAPTAPAI QKIEETVKME TEHLEEVEDS LAKFRVIEDW TGGSSSQEDE
       310        320        330        340        350        360
DVKVEVKTGS EAFYTMGGED NTTKAIRMYW IDAYEDVHKA NGTVYLFGKV KTSGNAWETC
       370        380        390        400        410        420
SIVVKNICRK VYFMPRTKNL STGEESSLAE LHKEIGDVLR NKFNTHEFKC KMVEKELIRD
       430        440        450        460        470        480
ESFGYGCGTK SPLMEVLYPA EKGKLPSDLK GDTFSNTFNT SVTPLERLLI EKKFMGPGWI
       490        500        510        520        530        540
ELYNYSDPKA KTSNCKYEFE VDMEKMRNIK YLESSDAPPP TIKLLALNVV TTLNDRKDNE
       550        560        570        580        590        600
ICMISMLFNP KCDLAHPSGD SKDLKPKCLV TKPPGGSLPY DIQKRLETEK LSKFVKSVAN
       610        620        630        640        650        660
EKALLTLFLA MINEDEPDMI VGHDLSATIA LLVSRLEKLK LPNWSRISRL KRSINIGKIG
       670        680        690        700        710        720
HSKSGQWELT AGRMMLDSKL AAMELVKSRS FDLTELSQQI LGAERREIYA NEIPQLYVDS
       730        740        750        760        770        780
KDLISLINWS WNDLLLSLRI VVRLNALPLY IQISQIVGGI ASRTMMGGRA ERNEYLLLHA
       790        800        810        820        830        840
FEKADLIAPD KYNSSESKKK KEESQEGDEK KSGKAQYSGG LVLEPKKGLY ETLILLLDFN
       850        860        870        880        890        900
SLYPSIIQEY NICYTTLEYS KDSDEQLSVP QSTDIEGVLP REIRKLVECR RDVKSLMKSE
       910        920        930        940        950        960
RNEAKKKQMD IRQMALKLTA NSMYGCLGFQ YSRFYAKPLA ALVTAKGREI LMHSKDLVEK
       970        980        990       1000       1010       1020
MGYSVVYGDT DSIMINTNSV DLVAAKKLGN EIKKAVNKCH RLLELDLDGV FKRMLLLKKK
      1030       1040       1050       1060       1070       1080
KYAALTINPD TKVEAKELKG LDIVRRDWSQ LAKETGTAVV DKILDASLTR DEMVSSIDDL
      1090       1100       1110       1120       1130       1140
LREIRAKLDS GTVPLEMFQI SKQLTRNPEQ YADVKAQCHA AVAQRLNKSG KFNLRHNDIV
      1150       1160       1170       1180       1190       1200
EYVICEDGTD NPATQRAYHR TEMAENSALK IDLLYYLAQQ IHPVVSRLVE PIEETDAVRI
      1210       1220       1230       1240       1250       1260
AENLGLDSTN YRRAAAAQAS QRAAEEDCAW HQENYDLCEG IHVICPLDGC GHSNVIRETF
      1270       1280       1290       1300       1310       1320
DCVTDASSPR LLFSGCAQCQ GSWDLQEHQA VIGNQVDRQM SEFVARHHLA AFKCDEPTCE
      1330       1340       1350       1360       1370       1380
FKTRVQTMKW CREGLECIRC STGVLRREYT SKQLFDQQMF FRTILDVDAA VRKLSDAQKK
      1390       1400       1410       1420
AAKVRVEYNG CKIDSMMLAD RINEKYLEKN AYNRVDLSYI FAPMMKIQ 

Encoded by gid:176544 gene


Nucleic acid sequence

        10         20         30         40         50         60
atgtccgact cggaaaacca tgcagaatcg gatgttagac gctcgtctcg ccgctgtgga
        70         80         90        100        110        120
gtcagtcaaa agaagtcgaa ggagctgtct gcaattgagc agctgaaatt ggcgcgatca
       130        140        150        160        170        180
acaggaaaag cctatcgccc agagctcgac gtggaggacg tctacgacac ggttgatgat
       190        200        210        220        230        240
gatgagtacg agaaaatcgt tgcaaaacga caaaaggaca attttattgt cgatgatgat
       250        260        270        280        290        300
ggaatgggct acgtagacaa cggtgtagac tttgaagatg actacgaaga cgattatgcg
       310        320        330        340        350        360
cccagttctt cgaaaaattc aaattcctcg aaaaaaggcg agaaaaagcc gaaaaaagac
       370        380        390        400        410        420
aagaaaaagg gaggacttca tgcattcctc tccacaacct ccaccaagaa gccgatcgac
       430        440        450        460        470        480
gagtctgtgg tgaaagccga gtttgacgac gatgaggagg tgaaaaatat gctggagcag
       490        500        510        520        530        540
ctgggaagca gcgatgagga ggccgaggag aagccgaagg cgaccccagc gaatccgttc
       550        560        570        580        590        600
aagcggggac gaaaattcga ctcaccgagc ggctcggatt cactggctcc acggccgatt
       610        620        630        640        650        660
gctaagaagg ccaagagaga ggcgaccggg ctcgccgagc acaaattcca gcggcatgtg
       670        680        690        700        710        720
aaggttgatg aggatgagga ttatgggatt ccagatgatt atccagtggc ttctccggtg
       730        740        750        760        770        780
acttctccag tgaaaacgga gaaaatggca gaagtcgaag ctccaacagc tccagcgatc
       790        800        810        820        830        840
cagaaaatcg aagaaacagt gaaaatggag accgagcatc tggaagaagt cgaggatagt
       850        860        870        880        890        900
ctggcgaagt tccgtgtcat tgaagactgg acaggcggga gcagcagtca ggaggacgaa
       910        920        930        940        950        960
gatgtgaagg tcgaggtgaa aaccggatcc gaagccttct acacgatggg cggcgaggac
       970        980        990       1000       1010       1020
aacaccacca aagcgatccg tatgtactgg atcgatgcct acgaggatgt tcacaaggcc
      1030       1040       1050       1060       1070       1080
aacggcaccg tctatctctt cggaaaggtc aaaaccagcg gtaacgcctg ggagacctgc
      1090       1100       1110       1120       1130       1140
tcaatcgttg tgaagaacat ctgcaggaag gtctacttta tgcctcgcac caagaatctc
      1150       1160       1170       1180       1190       1200
agcaccggag aggagtcgag ccttgccgag cttcacaagg agatcggaga tgttctgcgg
      1210       1220       1230       1240       1250       1260
aacaagttca acacacacga gttcaagtgt aagatggtgg agaaggagct gatccgtgac
      1270       1280       1290       1300       1310       1320
gagagcttcg gctacggatg cggcacgaag agcccgttga tggaagtgct ctatccggcg
      1330       1340       1350       1360       1370       1380
gagaagggga agcttcccag tgatcttaag ggtgacacat tctccaacac cttcaacaca
      1390       1400       1410       1420       1430       1440
tcagtcactc cgttggaacg gttgcttatt gaaaagaaat ttatgggtcc tggatggatt
      1450       1460       1470       1480       1490       1500
gagctgtata actattcgga tcccaaagcg aagacctcga attgcaagta tgagtttgag
      1510       1520       1530       1540       1550       1560
gttgatatgg agaagatgcg gaatatcaag tatctggaat cctctgacgc accaccgccg
      1570       1580       1590       1600       1610       1620
acgatcaagc ttctcgccct gaacgttgtc acaacgctca acgatcggaa ggacaatgag
      1630       1640       1650       1660       1670       1680
atttgcatga tttcgatgct tttcaatccg aaatgcgact tggctcatcc gagtggtgat
      1690       1700       1710       1720       1730       1740
agtaaggatt tgaagccgaa atgcctcgtc acaaagcctc ccggtggatc tctcccctat
      1750       1760       1770       1780       1790       1800
gacatccaaa agcgcttgga aactgagaaa ctctcgaaat tcgtgaaaag tgttgctaat
      1810       1820       1830       1840       1850       1860
gagaaggcac tgctcaccct gttcctggcg atgatcaatg aagatgaacc tgatatgatt
      1870       1880       1890       1900       1910       1920
gtgggacacg acttgtcggc gacaattgcc ttgttggttt caagacttga aaagctcaag
      1930       1940       1950       1960       1970       1980
ctgccgaatt ggtctagaat ttctcgttta aaacggtcaa ttaatattgg aaaaatcgga
      1990       2000       2010       2020       2030       2040
cattcaaaat caggccaatg ggagctcaca gcggggagaa tgatgttgga ctcgaagctt
      2050       2060       2070       2080       2090       2100
gccgcgatgg aacttgttaa atctcgaagc tttgatctca cagagctctc tcaacagatc
      2110       2120       2130       2140       2150       2160
cttggagccg agcgccgtga gatttacgcc aatgagattc cgcagttgta cgtggattcc
      2170       2180       2190       2200       2210       2220
aaagatctga tcagtctgat caattggtct tggaacgatc ttctactatc acttcggatc
      2230       2240       2250       2260       2270       2280
gttgttcggc ttaacgctct gccactctac attcaaatct cgcagattgt cggtggaatc
      2290       2300       2310       2320       2330       2340
gcttcgagaa cgatgatggg aggacgtgcc gagaggaatg agtatctgtt gcttcacgcg
      2350       2360       2370       2380       2390       2400
ttcgaaaaag cggatctcat cgcaccggat aagtataata gctcggagag caagaaaaag
      2410       2420       2430       2440       2450       2460
aaggaggaga gccaagaagg agacgagaag aagagtggaa aagcacaata ttcgggtggt
      2470       2480       2490       2500       2510       2520
ctggtgttgg agccgaagaa gggactctat gagacattga tcttgctgct cgattttaat
      2530       2540       2550       2560       2570       2580
tcattgtatc caagcattat tcaagagtat aatatttgtt atacgacgtt ggagtactcg
      2590       2600       2610       2620       2630       2640
aaggacagcg acgagcagct ctcagtacca cagagcacag atatcgaagg agttctacca
      2650       2660       2670       2680       2690       2700
cgtgaaattc gaaagcttgt agaatgccgt cgagacgtga aatctcttat gaaaagcgaa
      2710       2720       2730       2740       2750       2760
cgaaatgagg caaaaaagaa gcaaatggat attcgtcaaa tggctttaaa actcactgcc
      2770       2780       2790       2800       2810       2820
aactcaatgt acggatgtct tggatttcag tattcaaggt tttacgcgaa gcctctagcg
      2830       2840       2850       2860       2870       2880
gcactggtaa ctgcaaaagg acgagaaatt ctgatgcatt caaaggatct tgtagagaaa
      2890       2900       2910       2920       2930       2940
atgggttatt ctgtagtcta tggagatacg gattcaatta tgattaatac gaattcagtg
      2950       2960       2970       2980       2990       3000
gatttggtgg cggcaaagaa gcttggaaat gagattaaaa aggctgttaa caagtgtcat
      3010       3020       3030       3040       3050       3060
cggctcttgg agcttgatct tgatggagtt tttaagcgaa tgttgctctt gaaaaagaag
      3070       3080       3090       3100       3110       3120
aagtacgccg cgttgacgat taatccggat acgaaggttg aggcgaaaga attgaaagga
      3130       3140       3150       3160       3170       3180
ttggatattg ttagaagaga ttggtcacag ttggctaagg agactggaac agccgtcgtc
      3190       3200       3210       3220       3230       3240
gacaagatcc ttgacgcttc actgacccgc gacgagatgg tctcatcgat cgatgatcta
      3250       3260       3270       3280       3290       3300
ctgcgtgaaa ttcgtgcaaa actggattct ggcacggttc cactggaaat gttccaaatt
      3310       3320       3330       3340       3350       3360
agcaagcagc taactcgaaa tcctgaacaa tatgccgatg tgaaggctca atgccatgcg
      3370       3380       3390       3400       3410       3420
gcagttgctc agcggcttaa taaaagtgga aaattcaatt tgaggcataa tgatattgtg
      3430       3440       3450       3460       3470       3480
gaatatgtca tttgtgaaga tggaactgat aatccggcaa cacaacgagc ctatcatcgg
      3490       3500       3510       3520       3530       3540
actgaaatgg ctgagaattc ggcacttaaa attgatctcc tctactatct ggctcaacaa
      3550       3560       3570       3580       3590       3600
attcatccag tcgtatcgcg gctcgtcgag cccatcgagg aaaccgacgc agtccgaatt
      3610       3620       3630       3640       3650       3660
gccgaaaatc tcggtctgga ttcgaccaat tatcgacgag ctgcggcggc tcaagcttca
      3670       3680       3690       3700       3710       3720
cagcgagcag cagaagaaga ttgcgcgtgg caccaagaga attatgattt gtgcgaagga
      3730       3740       3750       3760       3770       3780
attcatgtga tttgtccact cgatgggtgc ggtcattcaa atgtgattcg agagacattt
      3790       3800       3810       3820       3830       3840
gattgtgtga ctgatgcctc gtctccccgc cttctattct ccggatgtgc tcaatgtcaa
      3850       3860       3870       3880       3890       3900
ggatcatggg atcttcagga gcatcaagca gtgattggga atcaagttga ccgacaaatg
      3910       3920       3930       3940       3950       3960
tcggaattcg tcgccagaca tcatctcgca gcgtttaaat gcgatgagcc aacgtgtgaa
      3970       3980       3990       4000       4010       4020
ttcaaaactc gcgtacaaac gatgaaatgg tgtcgagaag gactcgaatg tattcgatgc
      4030       4040       4050       4060       4070       4080
tcaactggtg tgctccgtcg tgaatacact tcaaaacagc ttttcgatca gcaaatgttc
      4090       4100       4110       4120       4130       4140
tttcgaacaa ttctcgatgt cgacgcggct gtacgaaagt tgagcgacgc ccagaaaaaa
      4150       4160       4170       4180       4190       4200
gccgccaaag tccgtgtcga atataatggg tgcaaaatcg attcaatgat gttggctgat
      4210       4220       4230       4240       4250       4260
cgaatcaatg agaaatattt ggagaaaaat gcctataatc gagtggatct ttcatatatt
      4270       4280
tttgcgccaa tgatgaaaat tcaatga   

Last modification date: Oct. 6, 2011