Schizo-saccharomyces pombe Lindner (fission yeast) [SPO]

FULL NAME: ribonuclease H2 subunit B


DESCRIPTION:
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes (By similarity).

STRUCTURE SIMILARITY:
Belongs to the RNase H2 subunit B family.


SUBUNIT STRUCTURE:
Component of the RNase H2 complex (By similarity).


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MQGKIFILPK DSTNQQFVEL SHPLTGRPLR YLLTNDHLLQ ILQVGDSSKQ RSWFVGDHVV
        70         80         90        100        110        120
SDGYLYVCTP IDLLALVLPI IQELTWSRRK EPNRYVSFED FIEHFDNMGP HYPRVSEVLS
       130        140        150        160        170        180
PNLLNTLHRI CKVNEPVGSL PKTFQLDESS VVKILLRKAK VAQENLPPSI VTELKKQLAP
       190        200        210        220        230        240
LDLRTPLPQD LLELSCKWHA ASLVCEDLQP EWYNKLAYWQ EELAPLHAYT KNLEESRKIL
       250        260        270        280        290
VEKEALLNSK KRPQNSDITS SLLKKPNRKQ ATKKSKYFSG EGMTKISSFF TKK

Encoded by gid:2539891 gene


Nucleic acid sequence

        10         20         30         40         50         60
atgcagggaa agatattcat actacccaaa gattctacaa atcaacaatt tgttgaactc
        70         80         90        100        110        120
tcacatccct tgaccgggag accacttcgt tatttattaa caaacgatca ccttttacaa
       130        140        150        160        170        180
atccttcaag ttggggattc ttcaaaacaa aggtcttggt ttgtagggga tcatgtagta
       190        200        210        220        230        240
tcggacggat atctctatgt ttgcaccccg atagacttac tcgcgcttgt gcttccaatc
       250        260        270        280        290        300
attcaggaac ttacttggag tcgccggaaa gaaccgaatc gatatgtctc gtttgaagac
       310        320        330        340        350        360
ttcattgaac actttgataa tatgggtcct cattatccac gagtgtcaga agtcctctct
       370        380        390        400        410        420
ccgaatttgt tgaacacatt acatcggatt tgtaaagtaa acgagccagt aggatctttg
       430        440        450        460        470        480
cccaagacct ttcaactgga tgaatcttct gttgttaaaa ttttactaag gaaagccaag
       490        500        510        520        530        540
gttgctcaag aaaatcttcc ccctagtatt gtaaccgaac ttaaaaaaca gttagcgcct
       550        560        570        580        590        600
ttggacctcc gcacgccgct tccacaagat ttactagaat tgtcatgcaa gtggcatgcc
       610        620        630        640        650        660
gcttcattgg tttgtgaaga tcttcaacct gaatggtata acaaattagc ctactggcag
       670        680        690        700        710        720
gaagaattgg ccccactgca cgcttacact aaaaacttag aagaatcaag aaagattttg
       730        740        750        760        770        780
gtagaaaagg aagctttgtt aaattctaaa aaacgtccac aaaacagtga tattacatca
       790        800        810        820        830        840
agtcttttaa aaaagcccaa tcggaagcag gccaccaaga agtccaaata cttctcagga
       850        860        870        880
gaaggaatga cgaaaatatc ttcattcttt acaaaaaagt aa 

Last modification date: Oct. 7, 2011