Schizo-saccharomyces pombe Lindner (fission yeast) [SPO]

FULL NAME: Proliferating cell nuclear antigen


DESCRIPTION:
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

STRUCTURE SIMILARITY:
Belongs to the PCNA family.


RELATED PATHWAY(S):
DNA replication
base excision repair (BER)
nucleotide excision repair (NER)
mismatch repair (MMR)


Amino acids sequence

        10         20         30         40         50         60
MLEARFQQAA LLKKLLDAIK ELVTDANFDC NDNGISLQAM DSSHVALVSM LIKSDGFEPY
        70         80         90        100        110        120
RCDRNIALGI NLNALSKVLR CAQNEDLVTL KAEDTPEVLN LVFESEKNDR ISDYDVKLMD
       130        140        150        160        170        180
IDQEHLGIPD IEYDATITMP AAEFQRITRD LLTLSDSVTI NASKEGVRFS CKGDIGNGST
       190        200        210        220        230        240
TLKQHTDLSD QDQSIEISLT QAVTLTFSLK YLAQFTKATP LATRVTLSMS NDVPLLVEYK
       250        260
MESGFLRFYL APKIGEEDEE    

Encoded by pcn1 gene


Nucleic acid sequence

        10         20         30         40         50         60
atgcttgaag ctagatttca gcaggctgct ttgttgaaaa agcttctcga tgccatcaag
        70         80         90        100        110        120
gagttagtta cagatgctaa ttttgattgc aatgacaacg gtatctctct gcaggctatg
       130        140        150        160        170        180
gatagttctc atgtagccct tgtttctatg cttattaaat cagatggatt tgaaccatat
       190        200        210        220        230        240
cggtgtgata gaaatattgc tttaggtata aatctgaacg ccttatcaaa ggtcttacgg
       250        260        270        280        290        300
tgtgcccaaa acgaggattt ggttacttta aaggctgaag atacacctga ggtattgaat
       310        320        330        340        350        360
ttggttttcg agagcgagaa aaatgacagg atctctgatt atgatgttaa attaatggac
       370        380        390        400        410        420
attgatcaag aacacttggg tataccagat atcgaatacg atgctactat tactatgcct
       430        440        450        460        470        480
gctgccgaat ttcaacgcat tactcgagat ttattaactt tgagtgattc agtaacaatc
       490        500        510        520        530        540
aatgctagta aagagggtgt tcgttttagc tgcaagggag atattggtaa tggtagtacc
       550        560        570        580        590        600
acgctgaaac aacataccga tctttctgac caagatcaaa gtatcgaaat ttctcttacc
       610        620        630        640        650        660
caagctgtaa cacttacgtt ttctttgaaa tatttagccc agttcactaa ggctactcct
       670        680        690        700        710        720
ttagctaccc gagtcacact ttcaatgagc aatgatgttc cacttcttgt ggagtataaa
       730        740        750        760        770        780
atggaatccg gatttttacg attttatctt gccccaaaaa ttggtgagga ggatgaggag

tag     

Last modification date: Oct. 2, 2011