Schizo-saccharomyces pombe Lindner (fission yeast) [SPO]

FULL NAME: Replication factor A protein 2


DESCRIPTION:
Binds to single-stranded sequences.

POST-TRANSLATIONAL MODIFICATION:
Phosphorylated in a cell cycle-dependent manner. Hypophosphorylated in G1, becomes phosphorylated at the G1/S boundary, it is maintained in this state through the M phase.


RELATED PATHWAY(S):
DNA replication
nucleotide excision repair (NER)
mismatch repair (MMR)
homologous recombination (HR)
Fanconi anemia (FA) pathway


Amino acids sequence

        10         20         30         40         50         60
MAYDAFGKPG YGPDFNSAFS PGMGGGAGFN EYDQSSQPSV DRQQGAGNKL RPVTIKQILN
        70         80         90        100        110        120
ASQVHADAEF KIDGVEVGQV TFVGVLRNIH AQTTNTTYQI EDGTGMIEVR HWEHIDALSE
       130        140        150        160        170        180
LATDTYVRVY GNIKIFSGKI YIASQYIRTI KDHNEVHFHF LEAIAVHLHF TQKANAVNGA
       190        200        210        220        230        240
NAPGYGTSNA LGYNNISSNG AANSLEQKLA EYSLTPAQMT VMQAIHSAPE TNEGVHVRQL
       250        260        270
AQSVGPGIDL TAVTDFLQQE GIIYTTIDEN HFKSVLQDQ  

Encoded by ssb2 gene


Nucleic acid sequence

        10         20         30         40         50         60
atggcttatg atgcttttgg caagccgggc tatggtcccg acttcaatag cgctttttct
        70         80         90        100        110        120
ccaggaatgg gaggaggcgc tggatttaat gaatatgatc aatcgagcca gcccagcgtc
       130        140        150        160        170        180
gatagacaac aaggagctgg aaataaatta cgtcctgtta ccattaagca aattctcaat
       190        200        210        220        230        240
gcctctcaag ttcacgctga tgcagaattc aagatagatg gcgttgaagt cggacaggtt
       250        260        270        280        290        300
acttttgtag gagttttacg gaacattcac gctcaaacta caaacacaac atatcaaata
       310        320        330        340        350        360
gaagatggaa caggaatgat tgaagtaagg cattgggaac acattgatgc gctatctgaa
       370        380        390        400        410        420
cttgctacag acacctatgt tcgtgtgtat ggaaacatca aaatattttc tggaaaaatt
       430        440        450        460        470        480
tacattgctt ctcaatacat ccgtacaatt aaagaccata atgaagtcca ttttcatttc
       490        500        510        520        530        540
cttgaagcaa ttgctgtaca cctacatttc actcagaaag caaatgctgt gaacggagcc
       550        560        570        580        590        600
aacgctccag gctacggaac ttccaacgca ctaggctaca ataacatttc ttcaaatggt
       610        620        630        640        650        660
gctgccaact ctctggaaca aaaactagct gaatattcac taacccccgc acaaatgacc
       670        680        690        700        710        720
gttatgcaag ctatccatag tgcaccagag acgaatgaag gtgttcacgt tagacaactt
       730        740        750        760        770        780
gctcaaagcg tgggtcccgg tatagacctt acggcggtta ctgattttct tcaacaagaa
       790        800        810        820        830        840
ggaatcatct acacaacaat tgatgaaaat cattttaaaa gtgttttaca agaccaataa

Last modification date: Oct. 2, 2011