TARGET: DNA-dependent DNA polymerase inhibitor

DESCRIPTION:
DNA-dependent DNA polymerase inhibitors are used to STOP the DNA synthesis: DNA replication or DNA repair synthesis (TLS) and DNA synthesis Rad6-dependent pathway.

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DRUG STRUCTURE OTHER TARGET TYPE(S) DNAtraffic related PROTEIN(S)
Aciclovir DNA
base analog
DNA-dependent DNA polymerase inhibitor
DNA synthesis inhibitor
Clofarabine DNA
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
base analog
DNA-dependent DNA polymerase inhibitor
Famciclovir DNA
anti-viral treatment
DNA-dependent DNA polymerase inhibitor
DNA synthesis inhibitor
Fludarabine anti-cancer treatment
DNA-dependent DNA polymerase inhibitor
DNA synthesis inhibitor
PRIM2
POLα (POLA)
Nevirapine deoxynucleic acid (DNA) synthesis inhibitor
anti-viral treatment
ribonucleic acid (RNA) synthesis inhibitor
reverse transcriptase inhibitor (RTI)
base analog
DNA-dependent RNA polymerase inhibitor
DNA-dependent DNA polymerase inhibitor
TERT (telomerase catalytic subunit)
Azelaic Acid anti-bacterial treatment
DNA-dependent DNA polymerase inhibitor
Ganciclovir DNA
anti-viral treatment
base analog
DNA-dependent DNA polymerase inhibitor
DNA synthesis inhibitor
Valaciclovir DNA
anti-viral treatment
base analog
DNA-dependent DNA polymerase inhibitor
Penciclovir DNA
anti-viral treatment
base analog
DNA-dependent DNA polymerase inhibitor
DNA synthesis inhibitor
Vidarabine DNA
anti-viral treatment
base analog
DNA-dependent DNA polymerase inhibitor
DNA synthesis inhibitor
Adefovir Dipivoxil DNA
anti-viral treatment
reverse transcriptase inhibitor (RTI)
base analog
DNA-dependent DNA polymerase inhibitor
DNA synthesis inhibitor
POLγ (POLG)
POLα (POLA)