TARGET: Purine nucleoside phosphorylase (PNP) inhibitor

DESCRIPTION:
Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules.

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DRUG STRUCTURE OTHER TARGET TYPE(S) DNAtraffic related PROTEIN(S)
8-Azaguanine anti-cancer treatment
purine nucleoside phosphorylase (PNP) inhibitor
base analog
Tubercidin DNA
RNA
deoxynucleic acid (DNA) synthesis inhibitor
anti-viral treatment
protein synthesis inhibitor
ribonucleic acid (RNA) synthesis inhibitor
purine nucleoside phosphorylase (PNP) inhibitor
Cladribine DNA
anti-cancer treatment
purine nucleoside phosphorylase (PNP) inhibitor
base analog
DNA repair inhibitor
DNA synthesis inhibitor