TARGET: Anti-cancer treatment

DESCRIPTION:
Chemotherapy (sometimes cancer chemotherapy) is the treatment of cancer with an antineoplastic drug or with a combination of such drugs into a standardized treatment regimen. The available anticancer drugs have distinct mechanisms of action which may vary in their effects on different types of normal and cancer cells.

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DRUG STRUCTURE OTHER TARGET TYPE(S) DNAtraffic related PROTEIN(S)
nifuroxazide anti-cancer treatment
anti-bacterial treatment
Valrubicin protein type
DNA
anti-cancer treatment
TOP2A
Cytarabine protein type
DNA
RNA
anti-cancer treatment
Plicamycin DNA
anti-cancer treatment
ribonucleic acid (RNA) synthesis inhibitor
Thioguanine DNA
RNA
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
ribonucleic acid (RNA) synthesis inhibitor
base analog
Cisplatin DNA
anti-cancer treatment
DNA repair inhibitor
DNA synthesis inhibitor
Floxuridine DNA
RNA
anti-cancer treatment
base analog
DNA synthesis inhibitor
RNA synthesis inhibitor
Mitomycin (MMC) DNA
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
Mechlorethamine DNA
anti-cancer treatment
DNA repair inhibitor
DNA synthesis inhibitor
RNA synthesis inhibitor
Cladribine DNA
anti-cancer treatment
purine nucleoside phosphorylase (PNP) inhibitor
base analog
DNA repair inhibitor
DNA synthesis inhibitor
Mycophenolate mofetil anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
Amsacrine DNA
anti-cancer treatment
DNA topoisomerase inhibitor
DNA repair inhibitor
DNA synthesis inhibitor
TOP2A
Zebularine anti-cancer treatment
base analog
nucleic acids methylation inhibitor
AICDA (AID)
APOBEC3G
AICDA (AID)
AidB
Bleomycin DNA
anti-cancer treatment
DNA repair inhibitor
DNA synthesis inhibitor
transcription inhibitor
Psammaplin A anti-cancer treatment
anti-bacterial treatment
DNA (cytosine-5)-methyltransferase inhibitor
nucleic acids methylation inhibitor
Camptothecin anti-cancer treatment
DNA-protein complex
DNA topoisomerase inhibitor
DNA repair inhibitor
DNA synthesis inhibitor
TOP1
RG108 anti-cancer treatment
DNA (cytosine-5)-methyltransferase inhibitor
nucleic acids methylation inhibitor
PROCAINAMINE anti-cancer treatment
DNA (cytosine-5)-methyltransferase inhibitor
nucleic acids methylation inhibitor
Busulfan DNA
anti-cancer treatment
DNA repair inhibitor
DNA synthesis inhibitor
transcription inhibitor
Temozolomide DNA
anti-cancer treatment
DNA repair inhibitor
DNA synthesis inhibitor
Procarbazine DNA
anti-cancer treatment
protein synthesis inhibitor
DNA synthesis inhibitor
transcription inhibitor
Decitabine DNA
RNA
anti-cancer treatment
other treatment
base analog
DNA (cytosine-5)-methyltransferase inhibitor
nucleic acids methylation inhibitor
Idarubicin DNA
anti-cancer treatment
DNA-protein complex
DNA topoisomerase inhibitor
DNA repair inhibitor
DNA synthesis inhibitor
TOP2A
Trabectedin DNA
anti-cancer treatment
DNA repair inhibitor
Fludarabine anti-cancer treatment
DNA-dependent DNA polymerase inhibitor
DNA synthesis inhibitor
PRIM2
POLα (POLA)
TOPOTECAN DNA
anti-cancer treatment
DNA-protein complex
deoxynucleic acid (DNA) synthesis inhibitor
DNA topoisomerase inhibitor
DNA repair inhibitor
DNA synthesis inhibitor
TOP1
Hydroxyurea anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
ribonucleic acid (RNA) synthesis inhibitor
DNA repair inhibitor
DNA synthesis inhibitor
Sodium stibogluconate anti-cancer treatment
other treatment
DNA topoisomerase inhibitor
DNA synthesis inhibitor
transcription inhibitor
TOP1
Dactinomycin DNA
anti-cancer treatment
transcription inhibitor
RNA synthesis inhibitor
Chlorambucil DNA
anti-cancer treatment
DNA repair inhibitor
DNA synthesis inhibitor
Raltitrexed anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
Nelarabine DNA
anti-cancer treatment
base analog
DNA synthesis inhibitor
Epirubicin DNA
anti-cancer treatment
DNA-protein complex
TOP2A
Azathioprine DNA
anti-cancer treatment
other treatment
DNA synthesis inhibitor
transcription inhibitor
Gemcitabine anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
Mercaptopurine anti-cancer treatment
ribonucleic acid (RNA) synthesis inhibitor
base analog
Hydroxystilbamidine Isethionate DNA
RNA
anti-cancer treatment
RNase inhibitor
Streptozocin DNA
anti-cancer treatment
anti-bacterial treatment
DNA synthesis inhibitor
Fluorouracil DNA
RNA
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
protein synthesis inhibitor
ribonucleic acid (RNA) synthesis inhibitor
base analog
DNA synthesis inhibitor
Methotrexate anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
Vinorelbine anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
Daunorubicin anti-cancer treatment
DNA-protein complex
TOP2A
Thiotepa DNA
anti-cancer treatment
IRINOTECAN anti-cancer treatment
DNA-protein complex
DNA topoisomerase inhibitor
DNA repair inhibitor
DNA synthesis inhibitor
TOP1
Oxaliplatin DNA
anti-cancer treatment
DNA repair inhibitor
DNA synthesis inhibitor
Teniposide protein type
anti-cancer treatment
TOP2A
Pentostatin DNA
RNA
anti-cancer treatment
Capecitabine RNA
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
Etoposide anti-cancer treatment
DNA-protein complex
DNA topoisomerase inhibitor
DNA repair inhibitor
DNA synthesis inhibitor
TOP2A
Lomustine DNA
RNA
anti-cancer treatment
Altretamine DNA
anti-cancer treatment
Azacitidine DNA
RNA
anti-cancer treatment
protein synthesis inhibitor
base analog
DNA synthesis inhibitor
DNA (cytosine-5)-methyltransferase inhibitor
nucleic acids methylation inhibitor
DNMT3B
DNMT1
Dnmt1
DNMT3A
Dnmt3a
Dnmt3b
Cyclophosphamide DNA
anti-cancer treatment
DNA repair inhibitor
DNA synthesis inhibitor
RNA synthesis inhibitor
Genistein anti-cancer treatment
DNA topoisomerase inhibitor
DNA synthesis inhibitor
TOP2A
Dacarbazine DNA
anti-cancer treatment
base analog
DNA repair inhibitor
DNA synthesis inhibitor
Gemtuzumab ozogamicin DNA
anti-cancer treatment
DNA repair inhibitor
Clofarabine DNA
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
base analog
DNA-dependent DNA polymerase inhibitor
8-Azaguanine anti-cancer treatment
purine nucleoside phosphorylase (PNP) inhibitor
base analog
Arsenic trioxide DNA
anti-cancer treatment
Cycloleucine RNA
anti-cancer treatment
nucleic acids methylation inhibitor
Ifosfamide DNA
anti-cancer treatment
DNA repair inhibitor
DNA synthesis inhibitor
Dexrazoxane protein type
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
TOP2A
Carboplatin DNA
anti-cancer treatment
DNA repair inhibitor
DNA synthesis inhibitor
Doxorubicin anti-cancer treatment
DNA-protein complex
deoxynucleic acid (DNA) synthesis inhibitor
DNA topoisomerase inhibitor
DNA repair inhibitor
DNA synthesis inhibitor
TOP2A
Uracil mustard DNA
anti-cancer treatment
Melphalan DNA
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
DNA repair inhibitor
DNA synthesis inhibitor
Pipobroman DNA
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
Methoxsalen DNA
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
Denileukin diftitox anti-cancer treatment
Estramustine DNA
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
DNA repair inhibitor
DNA synthesis inhibitor
Raloxifene anti-cancer treatment
transcription inhibitor
Carmustine DNA
RNA
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
protein synthesis inhibitor
ribonucleic acid (RNA) synthesis inhibitor
DNA synthesis inhibitor
Lucanthone DNA
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
DNA topoisomerase inhibitor
DNA repair inhibitor
DNA synthesis inhibitor
APEX1
TOP2A
TOP1
Vincristine DNA
anti-cancer treatment
deoxynucleic acid (DNA) synthesis inhibitor
DNA synthesis inhibitor