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Streptolydigin


ACCESSION NB: DB04785


TYPE: small molecule


GROUP: experimental

CATEGORIES:
Antibacterial Agents

PHARMACODYNAMICS:
Streptolydigin is an antibiotic which works by blocking nucleic acid chain elongation by binding to the polymerase, thus stopping RNA polymerase activity inside a cell. Specifically, it inhibits the assembly of the RNA polymerase II transcription complex and DNA polymerase III transcription. It is active against a number of gram positive bacteria.

AFECTED ORGANISMS:
Enteric bacteria and other eubacteria