Please note: Any medical or genetic information present in this entry is not intended as a diagnosis of your problem, but rather is provided as a helpful guide for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Information is not necessarily complete. Please see your doctor for diagnosis and treatment.

Please note: DNAtraffic database is the project under construction and information on this page is not finished yet.

Tubercidin


ACCESSION NB: DB03172 (EXPT03017)


TYPE: small molecule


GROUP: experimental


DESCRIPTION:
An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids. [PubChem]

VOLUME OF DISTRIBUTION: Not Available

CATEGORIES:
Antibiotics, Antineoplastic Antimetabolites, Antineoplastic Purine Nucleoside Phosphorylase inhibitor

ABSORPTION: Not Available

INDICATION:
Not Available

PHARMACODYNAMICS:
Not Available

MECHANISM OF ACTION:
Toxic adenosine analog with antiviral, antitrypanosomal, and antifungal functions. Inhibits multiple metabolic processes which includes: RNA processing, nucleic acid synthesis, protein synthesis, and methylation of tRNA through intracellular incorporation into nucleic acids. Acts as a plant antifungal, inhibits mammalian SAH hydrolase (SAHH), and blocks purine biosynthesis in Candida famata.

PROTEIN BINDING:
Not Available

TOXICITY:
Not Available

AFECTED ORGANISMS:
Not Available