Nervous system (NS) cancer

Brain & central nervous system (CNS) tumours can develop in either the brain or spinal cord, although spinal cord tumors are rare. Benign tumors and cancerous tumors at the site of origin are referred to as primary tumors. Tumors that develop somewhere other than the site of origin are called a metastatic tumors. More than 100,000 people in the United States are diagnosed with a brain tumor each year, and the numbers are increasing. In most cases, th cause for the brain tumor is unknown. Because of the incredible complexity of the human brain and its role in the normal function of the body, brain tumors often have incapacitating consequences.
p53 in glioma, KEGG entry H00042

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OMIM ID NAME PROTEINS TYPE ALIASES ABBREVIATIONS PATHWAY(S) RELATED
613029 glioma type 3 BRCA2 (FANCD1) nervous system (NS) cancer GLM3 Fanconi anemia (FA) pathway, homologous recombination (HR)
260500 choroid plexus papilloma TP53 nervous system (NS) cancer CPLPA DNA damage response (DDR)
276300 mismatch repair cancer syndrome (MMRCS) MSH2, MLH1, MSH6, PMS2 nervous system (NS) cancer, gastrointestinal (GI) cancer, blood cell cancer, risk of malignant disease, CANCER Turcot syndrome
brain tumor-polyposis syndrome 1
MMR DEFICIENCY
CHILDHOOD CANCER SYNDROM
BTP1 SYNDROME
MMRCS
BTPS1
Fanconi anemia (FA) pathway, mismatch repair (MMR)
162091 schwannomatosis (SCHWA) SMARCB1 (SNF5) nervous system (NS) cancer, CANCER congenital cutaneous neurilemmomatosis SCHWA chromatin remodeling

Last modification date: July 1, 2011