CANCER

Cancer (medical term: malignant neoplasm) is a class of diseases in which a group of cells display uncontrolled growth, invasion that intrudes upon and destroys adjacent tissues, and sometimes metastasis, or spreading to other locations in the body via lymph or blood. These three malignant properties of cancers differentiate them from benign tumors, which do not invade or metastasize.

Filter

Click on a column header name to sort

OMIM ID NAME PROTEINS TYPE ALIASES ABBREVIATIONS PATHWAY(S) RELATED
608232 chronic myeloid leukemia (CML) CANCER, blood cell cancer CHRONIC MYELOGENOUS LEUKEMIA
chronic granulocytic leukemia (CGL)
CML
CGL
600259 hereditary non-polyposis colorectal cancer, TYPE 4 PMS2 gastrointestinal (GI) cancer, risk of malignant disease, CANCER colorectal cancer, hereditary nonpolyposis, type 4 HNPCC4 Fanconi anemia (FA) pathway, mismatch repair (MMR)
600258 hereditary non-polyposis colorectal cancer, TYPE 3 PMS1 gastrointestinal (GI) cancer, risk of malignant disease, CANCER colorectal cancer, hereditary nonpolyposis, type 3 HNPCC3
613347 pancreatic cancer type 2 BRCA2 (FANCD1) risk of malignant disease, CANCER PNCA2 Fanconi anemia (FA) pathway, homologous recombination (HR)
211980 lung cancer TP53, ERCC6 (CSB) risk of malignant disease, CANCER LNCR nucleotide excision repair (NER), DNA damage response (DDR)
600678 hereditary non-polyposis colorectal cancer, TYPE 5 MSH6 gastrointestinal (GI) cancer, risk of malignant disease, CANCER colorectal cancer, hereditary nonpolyposis, type 5 HNPCC5 mismatch repair (MMR)
208900 ataxia-telangiectasia (AT) ATM neurodegenerative disease, blood cell cancer, psychomotor impairment, skeletal abnormalities, risk of malignant disease, chromosomal instability, immunodeficiency, sexual immaturity, sensitivity to radiation, CANCER, eye or vision problem Louis-Bar syndrome
AT, COMPLEMENTATION GROUP A, INCLUDED; ATA, INCLUDED
Boder-Sedgwick syndrome
AT
AT1
DNA damage response (DDR)
604395 hereditary non-polyposis colorectal cancer, TYPE 7 (HNPCC7) MLH3 gastrointestinal (GI) cancer, risk of malignant disease, CANCER HNPCC7 mismatch repair (MMR)
xxx9 cervical cancer CANCER
114500 COLORECTAL CANCER MSH2, MLH1, MLH3, MUTYH, MSH6, PMS2, PMS1, TP53 gastrointestinal (GI) cancer, risk of malignant disease, CANCER CRC Fanconi anemia (FA) pathway, base excision repair (BER), DNA damage response (DDR), mismatch repair (MMR)
609310 hereditary non polyposis colorectal carcinoma, TYPE 2 MLH1 gastrointestinal (GI) cancer, risk of malignant disease, CANCER colorectal cancer, hereditary nonpolyposis, type 2 HNPCC2 Fanconi anemia (FA) pathway, mismatch repair (MMR)
609265 Li-Fraumeni syndrome-2 CHEK2 (CHK2), TP53 risk of malignant disease, CANCER LFS2 DNA damage response (DDR)
xxx4 T-cell-prolymphocytic leukemia (T-PLL) ATM risk of malignant disease, CANCER, blood cell cancer T-cell chronic lymphocytic leukemia
"knobby" type of T-cell leukemia
T-prolymphocytic leukemia
T-cell lymphocytic leukemia
T-PLL
TPLL
DNA damage response (DDR)
613244 hereditary non-polyposis colorectal cancer, TYPE 8 (HNPCC8) MSH2 gastrointestinal (GI) cancer, risk of malignant disease, CANCER colorectal cancer, hereditary nonpolyposis, type 8 HNPCC8 mismatch repair (MMR)
xxx B-cell non-Hodgkin lymphomas (B-NHL) ATM CANCER, blood cell cancer B-NHL
NHL
BNHL
DNA damage response (DDR)
276300 mismatch repair cancer syndrome (MMRCS) MSH2, MLH1, MSH6, PMS2 nervous system (NS) cancer, gastrointestinal (GI) cancer, blood cell cancer, risk of malignant disease, CANCER Turcot syndrome
brain tumor-polyposis syndrome 1
MMR DEFICIENCY
CHILDHOOD CANCER SYNDROM
BTP1 SYNDROME
MMRCS
BTPS1
Fanconi anemia (FA) pathway, mismatch repair (MMR)
278720 xeroderma pigmentosum, complementation group C (XPC) XPC risk of malignant disease, skin problem, sensitivity to radiation, CANCER, skin cancer XERODERMA PIGMENTOSUM III
XP, GROUP C
XPC
XPCC
XP3
nucleotide excision repair (NER)
278780 xeroderma pigmentosum, complementation group G (XPG) ERCC5 (XPG) microcephaly, neurodegenerative disease, mental retardation (MR), risk of malignant disease, skin problem, sensitivity to radiation, CANCER, skin cancer xeroderma pigmentosum VII XPG
XP7
nucleotide excision repair (NER)
604370 breast-ovarian cancer familial type 1 (BROVCA1) BRCA1 breast cancer, CANCER BREAST-OVARIAN CANCER 1, FAMILIAL, SUSCEPTIBILITY
BREAST CANCER 1, FAMILIAL, SUSCEPTIBILITY
OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
BROVCA1 Fanconi anemia (FA) pathway
162091 schwannomatosis (SCHWA) SMARCB1 (SNF5) nervous system (NS) cancer, CANCER congenital cutaneous neurilemmomatosis SCHWA chromatin remodeling
612555 breast-ovarian cancer familial type 2 (BROVCA2) BRCA2 (FANCD1) blood cell cancer, risk of malignant disease, CANCER, breast cancer Fanconi anemia group D1 protein BROVCA2 Fanconi anemia (FA) pathway, homologous recombination (HR)
613348 pancreatic cancer, susceptibility to, 3 FANCN (PALB2) CANCER Fanconi anemia (FA) pathway
158320 Muir-Torre syndrome MSH2, MLH1 skin cancer, CANCER CUTANEOUS SEBACEOUS NEOPLASMS AND KERATOACANTHOMAS, MULTIPLE, WITH GASTROINTESTINAL AND OTHER CARCINOMAS MuToS
MTS
MRTES
Fanconi anemia (FA) pathway, mismatch repair (MMR)
609322 rhabdoid tumor predisposition syndrome type 1 (RTPS1) SMARCB1 (SNF5) CANCER malignant rhabdoid tumor RTPS1 chromatin remodeling
144700 renal cell carcinoma (RCC) hOGG1 CANCER RENAL CELL CARCINOMA, NONPAPILLARY RCC base excision repair (BER)

Last modification date: July 2, 2011