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prostate cancer

It is a malignancy originating in tissues of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma.

ABREVIATION(S):
PC

TYPE: risk of malignant disease

Related patway(s): Fanconi anemia (FA) pathway, DNA damage response (DDR)

DNAtraffic protein(s) related to disease: CHEK2 (CHK2), BRCA1, RNASEL

OMIM: 176807

Last modification date: Aug. 25, 2011