Damage sources

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DNA DAMAGE SOURCE DAMAGES
chloroethylene oxide 1,N6-etheno-A in (1εA) dsDNA
1,N6-etheno-A (1εA) in ssDNA
1,N6-etheno-A (1εA)
bischloroethyl nitrosourea (BCNU) 1,N6-ethano A (EA)
3,N4-ethano-C (EC)
intErstrand crosslinks (ICLs)
mitomycin C intErstrand crosslinks (ICLs)
intrAstrand crosslink
N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) N3-methyl G (3meG)
3-methyl A (3meA)
N7-methyl G (7meG)
O2-methyl T (O2meT)
3-methyl A (3-meA) in ssDNA
O2-methyl C (O2meC)
SN1 methylating agents N3-methyl G (3meG)
3-methyl A (3meA)
O6-methyl G (O6meG)
N7-methyl G (7meG)
O2-methyl T (O2meT)
3-methyl A (3-meA) in ssDNA
O2-methyl C (O2meC)
O4-methyl T (O4meT)
crotonaldehyde (CRA) 3,N4-alpha-OH-gamma-methyl-propano-C (mHPC)
intErstrand crosslinks (ICLs)
1,N2-alpha-methyl-gamma-OH-propano-G (mHPG)
propylene oxide (PPO) 1-propyl A (1pA)
N2-OH-propyl-G (hpG)
3-propyl C (3pC)
1-OH-propyl A (1hpA)
1-OH-propyl-G (hpG)
unstable adducts AP-site
benzo(a)pyrene diol epoxide adduct B[a]P-guanine
psoralen intErstrand crosslinks (ICLs)
DNA-psoralen
intrAstrand crosslink
abortive DNA ligation 5'-AMP end
SN2 methylating agents N3-methyl G (3meG)
3-methyl A (3meA)
N3-methyl T (3meT)
N3-methylT (3meT) in ssDNA
N7-methyl G (7meG)
N1-methyl A (1meA)
7-methyl A (7meA)
3-methyl A (3-meA) in ssDNA
3-methyl C (3meC)
acrolein (ACR) 1,N2-gamma-hydroxypropano-G (HPG)
3,N4-hydroxypropyl-C (HPC)
1,N6-alpha-hydroxypropano-A (HPA)
1,N2-alpha-hydroxypropano-G (HPG)
3,N4-alpha-HPC
intErstrand crosslinks (ICLs)
spontaneous deamination T:5-OH-U pair
5-hydroxy-U (5-OH-U)
dU in dsDNA
dU from U:G
dU in ssDNA
C:5-OH-U pair
hypoxanthine in DNA
A:5-OH-U pair
G:5-OH-U pair
uracil glycol (Ug)
deoxyuridine
cytosine glycol (Cg)
dU from U:A
cisplatin intErstrand crosslinks (ICLs)
intrAstrand crosslink
X-ray 3'-OH end
cancer chemotherapy 5-bromoU
5-fluoroU from 5-fluoroU:G
5-fluoroU from 5-fluoroU:A
3'-OH end
5'-TOP2 termini
5-fluoro-dU
intrAstrand crosslink
3'-TOP1 termini
3'-P
intErstrand crosslinks (ICLs)
3'-PUA termini
lipid peroxidation (LPO) 1,N2-beta-OH-ethano G (HEG)
M1A (OPA)
M1dG
N2-OH-propyl-G (hpG)
1,N2-etheno-G (1,2εG) in dsDNA
1,N6-etheno-A (1εA)
1,N2-gamma-hydroxypropano-G (HPG)
1,N6-alpha-hydroxyethano-A (HEA)
3,N4-hydroxypropyl-C (HPC)
1,N2-etheno-G (εG) in ssDNA
1,N2-alpha-hydroxypropano-G (HPG)
N2,3-etheno-G (N2,3-εG)
1,N2-propano-G (PG)
1-OH-propyl-G (hpG)
1,N6-etheno-A in (1εA) dsDNA
M3C
3,N4-alpha-OH-gamma-methyl-propano-C (mHPC)
M3dA
3,N4-ethano-C (EC)
1,N2-alpha-methyl-gamma-OH-propano-G (mHPG)
M1C (OPC)
1,N6-etheno-A (1εA) in ssDNA
1,N6-alpha-hydroxypropano-A (HPA)
M2G
reactive oxygen species (ROS) Tg from Tg:A
5-formyl dU from 5-formylU:G
8-hydroxyA (8-OH-A)
T:5-OH-U pair
FapyG from FapyG:T
5,6-dihydroxy U (5,6-diOH-U)
5-formyl dU (5-foU)
M1dG
8-oxoG from 8-oxoG:A
FapyG
5-hydroxy-6-hydro-T (5-OH-6-H-T)
5-hydroxy-U (5-OH-U)
5-hydroxymethyl U (5-OH-me-U)
FapyA
8-oxoG
8-oxodGTP
5-OH-meU from 5-OH-meU:A
FapyG from FapyG:C
FapyG from FapyG:G
thymine glycol (Tg)
C:5-OH-U pair
5-OH-meU from 5-OH-meU:G
5-hydroxy-6-hydro-C (5-OH-6-H-C)
5,6-dihydroxy C (5,6-diOH-C)
Tg from Tg:G
2-hydroxy-A (2-OH-A)
2-oxoA from 2-oxoA:G
FapyG:A
5,6-dihydro U (5,6-diH-U)
5-hydroxy C (5-OH-C)
8-oxoG from 8-oxoG:C
A:5-OH-U pair
G:5-OH-U pair
5-hydroxy-6-hydro-U (5-OH-6-H-U)
uracil glycol (Ug)
3,N4-ethenoC (εC) in ssDNA
2-oxoA
8-oxodGDP
Fapy-7meG
8-oxoA
3'-PUA termini
A from A:8-oxoG
5-OH-meU in ssDNA
cytosine glycol (Cg)
benzopyrene B[a]P-guanine
DNA replication errors T:5-OH-U pair
8-oxoG from 8-oxoG:A
dU in dsDNA
A from A:C
dU in ssDNA
8-oxoG from 8-oxoG:T
A from A:G
C:5-OH-U pair
8-oxoG from 8-oxoG:G
T from T:T
Tg from Tg:G
T from T:G
8-oxoG from 8-oxoG:C
G:5-OH-U pair
deoxyuridine
ionizing radiation (IR) Tg from Tg:A
T:5-OH-U pair
5,6-dihydroxy U (5,6-diOH-U)
5-hydroxy-6-hydro-T (5-OH-6-H-T)
5-hydroxy-U (5-OH-U)
5-hydroxymethyl U (5-OH-me-U)
8-oxoG
5-OH-meU from 5-OH-meU:A
thymine glycol (Tg)
C:5-OH-U pair
5-OH-meU from 5-OH-meU:G
5-hydroxy-6-hydro-C (5-OH-6-H-C)
5,6-dihydroxy C (5,6-diOH-C)
Tg from Tg:G
5,6-dihydro U (5,6-diH-U)
5-hydroxy C (5-OH-C)
A:5-OH-U pair
G:5-OH-U pair
5-hydroxy-6-hydro-U (5-OH-6-H-U)
5,6-dihydro T (5,6-diH-T)
uracil glycol (Ug)
5-OH-meU in ssDNA
cytosine glycol (Cg)
UV radiation FapyG:A
FapyG
FapyA
(6-4)PP
thymine glycol (Tg)
cytosine glycol (Cg)
CPD
vinyl chloride metabolites 1,N6-etheno-A in (1εA) dsDNA
3,N4-ethano-C (EC)
1,N2-etheno-G (1,2εG) in dsDNA
3,N4-etheno-C (εC) in dsDNA
1,N6-etheno-A (1εA)
1,N6-alpha-hydroxyethano-A (HEA)
Fapy-7meG from Fapy-7meG:C
1,N2-etheno-G (εG) in ssDNA
1,N6-etheno-A (1εA) in ssDNA
N2,3-etheno-G (N2,3-εG)
OEG
FapyG from FapyG:C
3,N4-ethenoC (εC) in ssDNA
DNA methyltransferase 5-methyl C (5meC)
N,4-methyl C in 5'-CAGCTG-3'
N-methyl-N-nitrosourea (NMU) 3-methyl A (3meA)
O2-methyl T (O2meT)
3-methyl A (3-meA) in ssDNA
O2-methyl C (O2meC)
MePT
O4-methyl T (O4meT)
benzene p-BQ-A
p-BQ-C
p-BQ-G
trans-4-hydroxy-2-nonenal (HNE) 1,N2-beta-OH-ethano G (HEG)
intErstrand crosslinks (ICLs)
M1C (OPC)
malondialdehyde (MDA) M1A (OPA)
M3C
M1dG
M3dA
M1C (OPC)
M2G
methyl radicals Fapy-7meG from Fapy-7meG:C
8-methyl G (8meG)
ethyl methanesulfonate (EMS) 1-ethyl A (1etA)
3-ethyl C (3etC)
O6-ethyl G (O6etG)
N-ethyl-N-nitrosourea (ENU) 1-ethyl A (1etA)
3-ethyl C (3etC)
O6-ethyl G (O6etG)
methyl methanesulfonate (MMS) N3-methyl G (3meG)
3-methyl A (3meA)
N3-methyl T (3meT)
N3-methylT (3meT) in ssDNA
N7-methyl G (7meG)
1-methyl G (1meG)
N1-methyl A (1meA)
7-methyl A (7meA)
3-methyl A (3-meA) in ssDNA
3-methyl C (3meC)
aflatoxin aflatoxin-G
aflatoxin-FapyG
methyl chloride N1-methyl A (1meA)
3-methyl C (3meC)
methyl bromide 5-bromoU
N1-methyl A (1meA)
3-methyl C (3meC)
methyl iodide N1-methyl A (1meA)
3-methyl C (3meC)
alkylating agents O6-ethyl G (O6etG)
1-OH-propyl A (1hpA)
N3-methyl T (3meT)
O2-methyl T (O2meT)
3-methyl C (3meC)
O2-methyl C (O2meC)
MePT
O4-methyl T (O4meT)
3-methylC (3meC) in RNA
N3-methyl G (3meG)
1-ethyl A (1etA)
1-propyl A (1pA)
3-methyl A (3meA)
3-ethyl C (3etC)
3-propyl C (3pC)
O6-methyl G (O6meG)
Fapy-7meG from Fapy-7meG:C
N3-methylT (3meT) in ssDNA
N7-methyl G (7meG)
1-methyl G (1meG)
N1-methyl A (1meA)
7-methyl A (7meA)
3-methyl A (3-meA) in ssDNA
3-methylC (3meC) in ssDNA
streptozotocin 3-methyl A (3meA)
N7-methyl G (7meG)
3-methyl A (3-meA) in ssDNA
chloroacetaldehyde (CAA) 1,N6-etheno-A in (1εA) dsDNA
1,N2-etheno-G (1,2εG) in dsDNA
3,N4-etheno-C (εC) in dsDNA
1,N6-etheno-A (1εA)
1,N6-alpha-hydroxyethano-A (HEA)
1,N2-etheno-G (εG) in ssDNA
1,N6-etheno-A (1εA) in ssDNA
N2,3-etheno-G (N2,3-εG)
3,N4-ethenoC (εC) in ssDNA
repair intermediate AP-site
5'-AMP end
3'-TOP1 termini
3'-OH end
5'-P end
5'-TOP2 termini
3'-P
3'-PUA termini
5'-dRP termini
ethylene oxide (EtO) 1,N6-etheno-A (1εA)
N1-OH-ethyl A (1heA)
1,N6-etheno-A in (1εA) dsDNA
1,N6-etheno-A (1εA) in ssDNA
nitrogen mustard intErstrand crosslinks (ICLs)
intrAstrand crosslink