abortive DNA ligation


OTHER NAMES:
5′ adenylated DNA
5'-AMP termini


ABBREVIATIONS:
5'-AMP


DESCRIPTION: 5′ adenylated DNA, a ligation intermediate which can accumulate at DNA breaks with 3′deoxy termini and ‘dirty’ breaks induced by oxidative DNA damage.

DNA DAMAGES:
5'-AMP end


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NAME STRUCTURE PROTEINS DNA DAMAGE EFFECT(S) PATHWAY(S) RELATED
5'-AMP end APTX cell cycle arrest
cytotoxic

Last modification date: Aug. 14, 2011