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NAME STRUCTURE PROTEINS DNA DAMAGE SOURCE(S) PATHWAY(S) RELATED
AP-site Nfo (endo IV)
APEX1
APEX2
XthA (exo III)
TDP1
UvrC
UvrB
DDB2 (XPE)
unstable adducts
repair intermediate
nucleotide incision repair (NIR)
base excision repair (BER)
nucleotide excision repair (NER)
prokaryotic (SOS) response
p-BQ-A UvrC
UvrB
ERCC5 (XPG)
ERCC4 (XPF)
benzene Fanconi anemia (FA) pathway
nucleotide excision repair (NER)
prokaryotic (SOS) response
5-bromoU TDG cancer chemotherapy
methyl bromide
base excision repair (BER)
5-fluoroU from 5-fluoroU:G MBD4 (MED1) cancer chemotherapy base excision repair (BER)
heterochromatin formation
5-fluoroU from 5-fluoroU:A SMUG1 cancer chemotherapy base excision repair (BER)
aflatoxin-G UvrC
UvrB
ERCC5 (XPG)
ERCC4 (XPF)
aflatoxin Fanconi anemia (FA) pathway
nucleotide excision repair (NER)
prokaryotic (SOS) response
O6-ethyl G (O6etG) MGMT ethyl methanesulfonate (EMS)
N-ethyl-N-nitrosourea (ENU)
alkylating agents
direct reversal (DR)
N3-methyl T (3meT) FTO
AlkB
SN2 methylating agents
methyl methanesulfonate (MMS)
alkylating agents
direct reversal (DR)
1,N2-gamma-hydroxypropano-G (HPG) acrolein (ACR)
lipid peroxidation (LPO)
5'-TOP2 termini TDP2 cancer chemotherapy
repair intermediate
1,N2-alpha-hydroxypropano-G (HPG) acrolein (ACR)
lipid peroxidation (LPO)
p-BQ-C UvrC
UvrB
ERCC5 (XPG)
ERCC4 (XPF)
benzene Fanconi anemia (FA) pathway
nucleotide excision repair (NER)
prokaryotic (SOS) response
O2-methyl T (O2meT) AlkA N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)
SN1 methylating agents
N-methyl-N-nitrosourea (NMU)
alkylating agents
base excision repair (BER)
5-fluoro-dU UNG
TDG
MBD4 (MED1)
SMUG1
cancer chemotherapy base excision repair (BER)
heterochromatin formation
3-methyl C (3meC) AlkB
ALKBH2
ALKBH3
ANPG (MPG)
SN2 methylating agents
methyl methanesulfonate (MMS)
methyl chloride
methyl bromide
methyl iodide
alkylating agents
base excision repair (BER)
direct reversal (DR)
O2-methyl C (O2meC) AlkA N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)
SN1 methylating agents
N-methyl-N-nitrosourea (NMU)
alkylating agents
base excision repair (BER)
MePT Ada N-methyl-N-nitrosourea (NMU)
alkylating agents
direct reversal (DR)
O4-methyl T (O4meT) Ogt
Ada
MGMT
SN1 methylating agents
N-methyl-N-nitrosourea (NMU)
alkylating agents
direct reversal (DR)
N3-methyl G (3meG) AlkA
Tag
ANPG (MPG)
N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)
SN1 methylating agents
SN2 methylating agents
methyl methanesulfonate (MMS)
alkylating agents
base excision repair (BER)
5'-AMP end APTX abortive DNA ligation
repair intermediate
1-ethyl A (1etA) ALKBH2
AlkB
ALKBH3
ethyl methanesulfonate (EMS)
N-ethyl-N-nitrosourea (ENU)
alkylating agents
direct reversal (DR)
3-methyl A (3meA) AlkA
Tag
ANPG (MPG)
N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)
SN1 methylating agents
SN2 methylating agents
N-methyl-N-nitrosourea (NMU)
methyl methanesulfonate (MMS)
alkylating agents
base excision repair (BER)
3,N4-alpha-OH-gamma-methyl-propano-C (mHPC) Mug crotonaldehyde (CRA)
lipid peroxidation (LPO)
base excision repair (BER)
3-ethyl C (3etC) AlkB ethyl methanesulfonate (EMS)
N-ethyl-N-nitrosourea (ENU)
alkylating agents
direct reversal (DR)
3'-TOP1 termini TDP1 repair intermediate base excision repair (BER)
1,N2-alpha-methyl-gamma-OH-propano-G (mHPG) UvrC
UvrB
crotonaldehyde (CRA)
lipid peroxidation (LPO)
nucleotide excision repair (NER)
prokaryotic (SOS) response
3'-P APTX
APEX1
XthA (exo III)
Nfo (endo IV)
APEX2
PNKP (PNK)
repair intermediate nucleotide incision repair (NIR)
base excision repair (BER)
N1-methyl A (1meA) ALKBH3
AlkB
ALKBH2
ANPG (MPG)
SN2 methylating agents
methyl methanesulfonate (MMS)
methyl chloride
methyl bromide
methyl iodide
alkylating agents
base excision repair (BER)
direct reversal (DR)
3'-PUA termini XthA (exo III)
Nfo (endo IV)
Fpg (MutM)
Nei (endo VIII)
APTX
APEX1
APEX2
cancer chemotherapy
reactive oxygen species (ROS)
repair intermediate
nucleotide incision repair (NIR)
base excision repair (BER)
3-methyl A (3-meA) in ssDNA AlkA N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)
SN1 methylating agents
SN2 methylating agents
N-methyl-N-nitrosourea (NMU)
methyl methanesulfonate (MMS)
alkylating agents
streptozotocin
base excision repair (BER)
5'-dRP termini FEN1 (DNase IV)
POLβ (POLB)
DNA Pol I
RecJ
HMGB1
POLγ (POLG)
POLλ (POLL)
repair intermediate DNA replication
base excision repair (BER)
nucleotide excision repair (NER)
mismatch repair (MMR)
homologous recombination (HR)
non-homologous end-joining (NHEJ)
translesion synthesis (TLS)

Last modification date: July 3, 2011