8-oxoG from 8-oxoG:A

FULL NAME: 8-oxoG from 8-oxoG:A mismatch


DESCRIPTION:
During DNA replication 8-oxoG can form the Hoogsten base pair with adenine.

DAMAGE TYPE: mismatch


DNA DAMAGE SOURCE(S) (MAIN):
reactive oxygen species (ROS)


DNA DAMAGE SOURCE(S) (MINOR):
DNA replication errors


DNA DAMAGE EFFECT(S) (MAIN):
mutagenesis
point mutation
substitution


PATHWAYS:
base excision repair (BER)


DNA repair protein(s) related to damage:
MutY
hOGG1
NEIL2


Last modification date: Sept. 29, 2011