2-oxoA

FULL NAME: 2-oxo-adenine


DESCRIPTION:
It is a product of oxidative damage to DNA and has been shown to cause mutation.

DAMAGE TYPE: oxidative damage


DNA DAMAGE SOURCE(S) (MAIN):
reactive oxygen species (ROS)


DNA DAMAGE EFFECT(S) (MAIN):
mutagenesis
point mutation
substitution


PATHWAYS:
base excision repair (BER)


DNA repair protein(s) related to damage:
MUTYH
MutY


Last modification date: Oct. 8, 2011