p-BQ-C

FULL NAME: para-benzoquinone-cytosine


DAMAGE TYPE: bulky adduct


DNA DAMAGE SOURCE(S) (MAIN):
benzene


DNA DAMAGE EFFECT(S) (MAIN):
carcinogen
cell cycle arrest
cytotoxic
DNA backbone distortion
stalled replication fork


DNA DAMAGE EFFECT(S) (MINOR):
mutagenesis


PATHWAYS:
Fanconi anemia (FA) pathway
nucleotide excision repair (NER)
prokaryotic (SOS) response


DNA repair protein(s) related to damage:
UvrC
UvrB
ERCC5 (XPG)
ERCC4 (XPF)


Last modification date: Oct. 11, 2011