OEG

FULL NAME: 7-(2'-oxoethyl)guanine


DESCRIPTION:
OEG is the major vinyl chloride-induced adduct. However, it does not induce mutagenesis and is thus thought not to play a significant role in vinyl chloride-induced mutagenesis.

DAMAGE TYPE: DNA adduct


DNA DAMAGE SOURCE(S) (MAIN):
vinyl chloride metabolites


DNA DAMAGE EFFECT(S) (MAIN):
no mutagenesis


PATHWAYS:
nucleotide excision repair (NER)
prokaryotic (SOS) response


DNA repair protein(s) related to damage:
UvrC
UvrB


Last modification date: Oct. 1, 2011