5,6-dihydro U (5,6-diH-U)

FULL NAME: 5,6-dihyrouracil


DESCRIPTION:
A pyrimidone obtained by formal addition of hydrogen across the 5,6-position of uracil.

DAMAGE TYPE: hydrate


DNA DAMAGE SOURCE(S) (MAIN):
reactive oxygen species (ROS)
ionizing radiation (IR)


DNA DAMAGE EFFECT(S) (MAIN):
mutagenesis


PATHWAYS:
base excision repair (BER)


DNA repair protein(s) related to damage:
Nei (endo VIII)
NEIL2
Nth (endo III)


Last modification date: Oct. 9, 2011