M3C

FULL NAME: M3C DNA adduct


DAMAGE TYPE: bulky adduct


DNA DAMAGE SOURCE(S) (MAIN):
lipid peroxidation (LPO)
malondialdehyde (MDA)


DNA DAMAGE EFFECT(S) (MAIN):
carcinogen
mutagenesis


PATHWAYS:
Fanconi anemia (FA) pathway
nucleotide excision repair (NER)
prokaryotic (SOS) response


DNA repair protein(s) related to damage:
UvrC
UvrB
ERCC5 (XPG)
ERCC4 (XPF)


Last modification date: Oct. 12, 2011