B[a]P-guanine

FULL NAME: benzo-a-pyren guanine


DAMAGE TYPE: bulky adduct


DNA DAMAGE SOURCE(S) (MAIN):
benzo(a)pyrene diol epoxide adduct
benzopyrene


DNA DAMAGE EFFECT(S) (MAIN):
-2 frameshift
mutagenesis
stalled replication fork


PATHWAYS:
Fanconi anemia (FA) pathway
nucleotide excision repair (NER)
prokaryotic (SOS) response


DNA repair protein(s) related to damage:
UvrC
UvrB
ERCC5 (XPG)
ERCC4 (XPF)


Last modification date: Dec. 15, 2011