M1A (OPA)

FULL NAME: N6-(3-oxo-propenyl)deoxyadenosine


DAMAGE TYPE: DNA adduct


DNA DAMAGE SOURCE(S) (MAIN):
lipid peroxidation (LPO)
malondialdehyde (MDA)


DNA DAMAGE EFFECT(S) (MAIN):
A→G transition
carcinogen
mutagenesis
transition


DNA DAMAGE EFFECT(S) (MINOR):
deletion
insertion
mutagenesis


PATHWAYS:
Fanconi anemia (FA) pathway
nucleotide excision repair (NER)
prokaryotic (SOS) response


DNA repair protein(s) related to damage:
UvrC
UvrB
ERCC5 (XPG)
ERCC4 (XPF)


Last modification date: Oct. 12, 2011