5'-TOP2 termini

FULL NAME: stalled topoisomerase II-DNA complexes


DAMAGE TYPE: strand break


DNA DAMAGE SOURCE(S) (MAIN):
cancer chemotherapy
repair intermediate


DNA DAMAGE EFFECT(S) (MAIN):
cell cycle arrest
cytotoxic


DNA DAMAGE EFFECT(S) (MINOR):
apoptosis


DNA repair protein(s) related to damage:
TDP2


Last modification date: Oct. 10, 2011