3'-OH end

FULL NAME: 3'-hydroxyl termini


DAMAGE TYPE: strand break


DNA DAMAGE SOURCE(S) (MAIN):
repair intermediate


DNA DAMAGE SOURCE(S) (MINOR):
X-ray
cancer chemotherapy


DNA DAMAGE EFFECT(S) (MAIN):
apoptosis
cell cycle arrest


DNA DAMAGE EFFECT(S) (MINOR):
stalled replication fork


PATHWAYS:
DNA replication
base excision repair (BER)
mismatch repair (MMR)
homologous recombination (HR)
Fanconi anemia (FA) pathway
nucleotide incision repair (NIR)


DNA repair protein(s) related to damage:
XthA (exo III)
Nfo (endo IV)
APEX1
APEX2
DnaQ
TREX2
TREX1 (DNase III)


Last modification date: Oct. 10, 2011